Results 71 to 80 of about 6,938,572 (266)
C1 Esterase Inhibitor (Human) for the Treatment of Acute Hereditary Angioedema
Clinical Medicine Insights: Blood Disorders, 2011 Hereditary angioedema (HAE) is a relatively rare disease characterized by acute episodes of swelling. These swellings can be disfiguring, painful and life-threatening.
Solange Oliveira Rodrigues Valle +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Sialkoti paper used by Pahari artists: raw materials and fibre analysis
Heritage ScienceThis study aims to characterise the so-called Sialkoti paper used to produce Pahari drawings preserved today in the Wereldmuseum in Leiden (Netherlands) (WML). These works originate from the Punjab Hills in India (today Himachal Pradesh) and are commonly
Amélie Couvrat Desvergnes +1 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ReligionsAround the figure of Zöhre Ana, a contemporary female mystic in Ankara, Turkey, considered by her followers a saint and known for her healing powers, has grown a substantial cult followed by hundreds if not thousands of devotees, with its own mythology ...
Mark Soileau
doaj +1 more source
Global Spine Journal, 2018 Study Design: Systematic review. Objectives: The objective of this systematic review was to answer 2 key questions: (1) What is the clinical presentation and probability of symptomatic improvement following treatment for patients with renal cell ...
C. Rory Goodwin MD, PhD +11 more
doaj +1 more source
Inference: International Review of Science, 2022 In the mid-1980s, an enigmatic document began circulating in French mathematical circles. Entitled Récoltes et Semailles, it was a lengthy, philosophical and deeply personal tract from the elusive mathematician Alexander Grothendieck, by then living in self-imposed seclusion.
openaire +2 more sources