Results 171 to 180 of about 6,428,242 (364)

A Manuscript Anthology of the Resolutions of Church Congresses (Sobory) and Other Essays of the Filippovtsy in the Collection of the Wróblewski Library, Lithuanian Academy of Sciences

, 2019
Nadežda Morozova
openalex   +2 more sources

Mircea Eliade’s Unpublished Manuscripts from Private Collections III. Notebooks I & II (Calcutta, 1929-1931). Commentary

, 2023
Eugen Ciurtin, Andreea Apostu
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Between research and introduction to clinical routine-Experience with niraparib from the compassionate use program in Germany (NOGGO Register Analysis). [PDF]

Arch Gynecol Obstet
Grabowski JP, Welz J, Heublein S, Krajewska M, Boer JD, Kraus F, Arndt T, Moosmann N, Heinrich B, Engler T, Agabejli S, Ugur MC, Witteler R, Albrecht O, Müller-Huesmann H, Oskay-Özcelik G, Hettwer C, Kaiser S, Braicu E, Sehouli J.   +19 more
europepmc   +1 more source

A Hidden Window into Cuban History: The Carl Withers Manuscript Collection at New York University

, 2010
E. Brown, Jorge L. Giovannetti
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Croaking for haste: How long does it take to describe a frog species since its discovery? [PDF]

PLoS One
Carné A, Sánchez-Vialas A, Lansac C, Moreno-Orosa M, De la Riva I.   +4 more
europepmc   +1 more source

Aleksandre Jaba’s Collection of Kurdish Folk Poetry Manuscripts and "Kilamê Kîçan" of the Kurd 49

, 2018
Mustafa Öztürk
openalex   +2 more sources

Ravenna letters of Fedir Schmit from the collection of manuscripts of the Central Library of the V. N. Karazin Kharkiv National University

, 2022
Maryna Domanovska, Iryna Kononenko
openalex   +2 more sources