Results 181 to 190 of about 9,793,739 (301)

Health-Related Quality of Life in The Chinese Cultural Context: A Scoping Review Protocol. [PDF]

Health Sci Rep
Liu S, Rawson H, Team V.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Academic entitlement and student well-being: The mediating role of the impostor phenomenon. [PDF]

PLoS One
Alsuwaylim AM, Alsharif BA, Abdellatif MS, Rahmath M, Ibrahim AR, Nemtallah MA.   +5 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

How knowledge translation interventions involving health policy decision makers are evaluated: a scoping review protocol. [PDF]

HRB Open Res
Phillips A, Macenaite M, Byrne M, Treweek S, Toomey E.   +4 more
europepmc   +1 more source

W-Manuscript

Electronic reproduction from Rulan Chao Pian Manuscript ...

core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Profiles of mental health indicators among Ukrainian people recently bereaved in the context of the full-scale Russian invasion. [PDF]

PLoS One
Pociūnaitė-Ott J, Boelen PA, Frankova I, Norkina I, Rispa Hoyos MLF, Lenferink LIM.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Artificial intelligence (AI) adoption and Chinese art teachers' career exploration behavior: The roles of job substitution risks, job insecurity, and organizational AI readiness. [PDF]

PLoS One
Li J, Gao Y.
europepmc   +1 more source