Results 221 to 230 of about 8,055,089 (291)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Introduction: Fitting Manuscript Studies into the Historical Network Research

Journal of Historical Network Research
Evina Stein, Gustavo Fernández Riva
doaj   +1 more source

Effects of scapular-focused movement-based exercises on sports performance of athletes with scapular dyskinesis: A systematic review. [PDF]

PLoS One
Solana-Tramunt M, Fakoor Rashid H, Norouzi N, Dehghan Y, Khazanin H, Sadegh B, Alimoradi M, Daneshmandi H, Alghosi M.   +8 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Comparative Oriental Manuscript Studies Newsletter

Archivalia, 2011
openaire   +2 more sources

Time requirements of pre-acclimatization at simulated altitude to prevent acute mountain sickness. [PDF]

J Travel Med
Burtscher J, Hüfner K, Gatterer H, Pichler-Hefti J, Hefti U, Tannheimer M, Kleinsasser A, Hackett P, Burtscher M.   +8 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Gastrointestinal Symptoms and Systemic Comorbidities in Patients With POTS: A Systematic Review and Meta-Analysis. [PDF]

Neurogastroenterol Motil
Kulin D, Shah A, Fairlie T, Staller K, Nurko S, Keefer L, Aziz Q, Drossman DA, Jones MP, Holtmann G.   +9 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Outcomes of hyperglycaemia in pregnancy in Africa: Systematic review and meta-analysis. [PDF]

PLoS One
Musa E, Chivese T, Werfalli M, Soepnel LM, Nicolaou V, Matjila M, Norris SA, Levitt NS.   +7 more
europepmc   +1 more source