Results 141 to 150 of about 1,535,370 (308)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Porrentruy, Bibliothèque cantonale jurassienne, A2037 : Composite manuscript containing texts on the history of the abbeys of Bellelay and Lucelle

open access: yes
This composite manuscript is dated 1839 (p. V2) and contains texts about the history of the abbeys of Bellelay and Lucelle; it was compiled by Joseph Trouillat when he was librarian at the college of Porrentruy: De Bellegagiensi monasterio (pp.
Joseph, Voirol, Grégoire
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 1002 : Humbertus de Romanis, De tribus votis substantialibus religionis in German. Jan van Ruusbroec, Brulocht in the Upper German tradition

open access: yes
This manuscript, which features two ownership notes from the community of sisters of St. Georgen above St. Gall (probably from the period around 1500) on p. 3, contains two spiritual texts from the 13th and 14th century, respectively.
Ruusbroec, Jan van   +1 more
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Basel, Universitätsbibliothek, A VIII 36 : Collection of hagiographic texts

open access: yes
This composite manuscript in German is from the Convent of Dominican nuns of St. Maria Magdalena “an den Steinen” in Basel, which was reformed in 1423; most of the manuscript was probably written there as well.
Biberli, Marquard   +1 more
core   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 731 : Lex Romana Visigothorum, Lex Salica, Lex Alamannorum

open access: yes
The Wandalgarius manuscript containing copies of the so-called Lex Romana Visigothorum, the Lex Salica and the Lex Alamannorum. This important legal manuscript, was written in Lyon in 793 and was decorated by the cleric Wandalgarius with numerous colored
Pater Pius Kolb   +2 more
core   +1 more source

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