Results 111 to 120 of about 166,756 (292)

Circulation Editors' Picks: most read articles in cardiovascular quality and outcomes

, 2013
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals.
The Editors,
core   +1 more source

Editor’s Note

Iranian Rehabilitation Journal, 2009
It is our pleasure to inform our Iranian Rehabilitation Journal readers and contributors that the journal had been indexed in IndexCopernicus Journals Master List which can be seen in http://journals.indexcopernicus.com/masterlist.php.
Asghar Dadkhah
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Circulation Editors' Picks: Most Read Articles in Cardiovascular Interventions

, 2011
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation
null null
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Space Syntax at Expression of Science on User Flows in Open and Closed Spaces Aimed at Achieving the Sustainable Development Goal: A Review

Architecture
Space syntax is utilized to model flows through open and closed built environments, which enables project innovation by rethinking the design of spaces on a global scale with better flow quality. Therefore, studies focused on spatial syntax, when related
Paulo Wladinir da Luz Leite, Caliane Christie Oliveira de Almeida Silva, Leila Dal Moro, Brian William Bodah, Giana de Vargas Mores, Dirceu Piccinato Junior, Amanda Engel, M. Santosh, Alcindo Neckel   +8 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Foreword of the second special issue on “Soil Governance”

Soil Security
This second special issue is an expression of what ten years ago nobody would have thought being possible: Soils have become what they deserve to be, a relevant topic on the global, regional, and national agendas of sustainability policies. Soils are now
Natalia Rodríguez Eugenio, Harald Ginzky, Irene L. Heuser, Ian Hannam, Oliver C Ruppel, Pamela Towela Sambo   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Manuscripts of Timbuktu, A Historical Look at the West African City, Its Manuscripts, and Islam, Turned into an Education Unit for High School Classes

The city of Timbuktu was often referred to as the “City of Gold”, as it has a kind of mythical status around it. Timbuktu is located in West Africa, modern day Mali, and is on the southern edge of the Sahara Desert.
Kamphues, Bryce
core