Results 121 to 130 of about 15,152,741 (289)
Many-Body Effects Determine the Local Hydration Structure of Cs+ in Solution
A systematic analysis of the hydration structure of Cs+ ions in solution is derived from simulations carried out using a series of molecular models built upon a hierarchy of approximate representations of many-body effects in ion-water interactions ...
Debbie Zhuang (6112614) +4 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Many Musics: Biscuits and Bluegrass Gospel Hour
On Sunday morning, join ETSU’s Bluegrass, Old Time, and Country Music Studies Program at the MANY MUSICS: BISCUITS & BLUEGRASS GOSPEL HOUR.
Biscuits and Bluegrass Gospel Hour, Many Musics:
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
MOOCs and Libraries: Many Hats, Many Questions
In light of their ubiquitous presence today, it is easy to forget: even if you date back to the first use of the term, MOOCs (massive open online courses) are only six years old.
Ashley E. Faulkner
doaj
Book synopsis: Southern Iraq, April 2003. Four soldiers, a journalist and their Iraqi translator set off on an unauthorised journey deep into the Iraqi countryside in a disastrous attempt to make amends for the deaths of some local men at a vehicle ...
Teevan, Colin
core
Many-Core Levels (MCL) is a framework that allows one to write computational kernels for different kinds of many-core ...
Hijma, Pieter +3 more
core +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

