Results 161 to 170 of about 2,289,454 (296)
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Western New Britain [cartographic material] : provisional map /
, 1943 1st rev. [ed.]. Topographic map of Western New Britain. Relief shown by contours and spot heights.; "This map supercedes previous edition printed in August 1943."; Includes index to adjoining sheets and reliability diagram.; Also available in an ...
United States. Army. South West Pacific Area. Base Map Plant.
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Bismarck Archipelago 1:50,000 [cartographic material] : provisional map /
, 1946 Various editions. Topographic map series of New Britain in the Bismarck Archipelago showing roads, trails, underwater obstructions, intermittent streams, villages, swamps, plantation, mangroves and jungles.
United States. Army. South West Pacific Area. Base Map Plant.
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
, 2015 The problem of map matching appears when evaluating GPS-tracks recorded by service vehicles, and utilizing GPS-information in graphs suitable for route optimization. The task is to associate sequences of GPS-points to links in a graph, suitable for optimization, and thereby obtain paths or tours in the graph.
openaire +1 more source
Lesser Sunda Islands 1:250,000 /
, 1943 Various editions. Topographic map series of Lesser Sunda Islands, Indonesia. Five classes of roads and trails, various types of air fields, and two types of internal boundaries are shown.; Elevations are shown by hachures or contours, and spot heights ...
United States. Army Map Service, cartographer.
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Tokyo and vicinity [cartographic material] : showing bombed-out areas /
, 1946 Town plan of Tokyo showing administrative and municipal boundaries, transportation, water features, religious, public and government buildings, built-up areas and sub-divisions of the chome.
Nippon Map (Firm)
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source