Results 161 to 170 of about 274,417 (276)

MAPK Pathways Coordinate Stress Adaptation by Mobilizing Specialized Gene Modules in Entomopathogenic Fungus <i>Beauveria bassiana</i>. [PDF]

J Fungi (Basel)
Huang S, Fan H, Zhu C, Li M, Liu L, Bai M, Zhou Y, Zhang Y.   +7 more
europepmc   +1 more source

DLK-1/p38 MAP Kinase Signaling Controls Cilium Length by Regulating RAB-5 Mediated Endocytosis in Caenorhabditis elegans

, 2015
Aniek van der Vaart, Suzanne Rademakers, Gert Jansen   +2 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Fusions4U: a resource of validated and annotated gene fusions in 328 cancer cell lines. [PDF]

BMC Cancer
Alamshahi A, Persson H.
europepmc   +1 more source

Enteroaggregative Escherichia coli flagellin‐induced interleukin‐8 secretion requires Toll‐like receptor 5‐dependent p38 MAP kinase activation

, 2004
Mohammed A. Khan, Jian Kang, Theodore S. Steiner   +2 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2. [PDF]

Elife
Chen S, Basiashvili T, Hutchings J, Sanz Murillo M, Villagran Suarez A, Xiong E, Alegrio Louro J, Leschziner AE, Villa E.   +8 more
europepmc   +1 more source

5 MPF AND MAP KINASES IN OVINE OOCYTES: EFFECTS OF ENUCLEATION AND CAFFEINE ON ACTIVITY AND DEVELOPMENT OF NUCLEAR TRANSFER EMBRYOS [PDF]

, 2004
Ji‐Hyun Lee, KHS Campbell
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Molecular mechanism of PINK1 regulation by the Hsp90 machinery. [PDF]

Nat Commun
Tian X, Su J, Wang Z, Liu T, Xiong H, Sun S, Mei K, Sui SF.   +7 more
europepmc   +1 more source