Results 11 to 20 of about 274,417 (276)

A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis [PDF]

open access: hybridJournal of Biological Chemistry, 2017
The mitogen-activated protein kinases (MAPKs) have been shown to regulate skeletal muscle function. Previously, we showed that MAPK phosphatase-5 (MKP-5) negatively regulates myogenesis and regeneration of skeletal muscle through inhibition of p38 MAPK and c-Jun N-terminal kinase (JNK).
Ho‐Jin Lee   +6 more
openalex   +4 more sources

Studies of the role of MAP kinase-activated protein kinase-5 (MK5) in reactive and reparative fibrosis in the murine heart

open access: green, 2017
MK5 est une sérine/thréonine kinase, identifiée à l'origine comme une protéine kinase régulée/activée par p38 (PRAK), activée par les p38 MAPK et MAPK atypiques ERK3 et ERK4. Bien que MK5 soit exprimée dans le cœur, sa fonction physiologique commence seulement à être étudiée.
Sherin A. Nawaito
openalex   +3 more sources

Synthesis and Biological Activities of 4-Phenyl-5-pyridyl-1,3-thiazole Derivatives as p38 MAP Kinase Inhibitors

open access: bronzeChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Seiji Miwatashi   +7 more
openalex   +4 more sources

MAP kinases differentially bind and phosphorylate NOS3 via two unique NOS3 sites

open access: yesFEBS Open Bio, 2022
Nitric oxide synthase 3 (NOS3) is a major vasoprotective enzyme that catalyzes the conversion of l‐arginine to nitric oxide (NO) in response to a significant number of signaling pathways.
Xzaviar K. V. Solone   +9 more
doaj   +1 more source

Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase. [PDF]

open access: yesPLoS ONE, 2012
In this study, microglial migration and phagocytosis were examined in mouse organotypic hippocampal slice cultures, which were treated with N-methyl-D-aspartate (NMDA) to selectively injure neuronal cells.
Takahiro Katayama   +8 more
doaj   +1 more source

Effect of Chitosan Composite Preservative on Proteome Changes of Grass Carp Muscle during Cold Storage [PDF]

open access: yesShipin Kexue, 2023
To explore the effect of a chitosan-based preservative solution (10 mg/mL chitosan + 5 mg/mL tea polyphenol + 2 000 U/mL lysozyme) on the change in the muscle proteome of grass carp during cold storage, differential proteomic analysis of fresh fish and ...
LI Jialei, CHEN Sai, TIAN Mingli, YU Jian, LIU Yongle, WANG Faxiang
doaj   +1 more source

Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor [PDF]

open access: yesOncogene, 1999
Interleukin (IL)-3, IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) regulate proliferation, differentiation and apoptosis of target cells. Receptors for these cytokines consist of a cytokine-specific alpha subunit and a common shared beta c subunit.
P F, Dijkers   +6 more
openaire   +2 more sources

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