MAP Kinase-Activated Protein Kinase 5 [PDF]
National Cancer Institute
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A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis [PDF]
The mitogen-activated protein kinases (MAPKs) have been shown to regulate skeletal muscle function. Previously, we showed that MAPK phosphatase-5 (MKP-5) negatively regulates myogenesis and regeneration of skeletal muscle through inhibition of p38 MAPK and c-Jun N-terminal kinase (JNK).
Ho‐Jin Lee +6 more
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MK5 est une sérine/thréonine kinase, identifiée à l'origine comme une protéine kinase régulée/activée par p38 (PRAK), activée par les p38 MAPK et MAPK atypiques ERK3 et ERK4. Bien que MK5 soit exprimée dans le cœur, sa fonction physiologique commence seulement à être étudiée.
Sherin A. Nawaito
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Regulator of G-protein signaling 5 (RGS5); MAP kinase kinase 1 (MAP2K1; MEK1); MAP kinase 3 (MAPK3; ERK-1); MAPK1 (ERK-2) [PDF]
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Seiji Miwatashi +7 more
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MAP kinases differentially bind and phosphorylate NOS3 via two unique NOS3 sites
Nitric oxide synthase 3 (NOS3) is a major vasoprotective enzyme that catalyzes the conversion of l‐arginine to nitric oxide (NO) in response to a significant number of signaling pathways.
Xzaviar K. V. Solone +9 more
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Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase. [PDF]
In this study, microglial migration and phagocytosis were examined in mouse organotypic hippocampal slice cultures, which were treated with N-methyl-D-aspartate (NMDA) to selectively injure neuronal cells.
Takahiro Katayama +8 more
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Effect of Chitosan Composite Preservative on Proteome Changes of Grass Carp Muscle during Cold Storage [PDF]
To explore the effect of a chitosan-based preservative solution (10 mg/mL chitosan + 5 mg/mL tea polyphenol + 2 000 U/mL lysozyme) on the change in the muscle proteome of grass carp during cold storage, differential proteomic analysis of fresh fish and ...
LI Jialei, CHEN Sai, TIAN Mingli, YU Jian, LIU Yongle, WANG Faxiang
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Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor [PDF]
Interleukin (IL)-3, IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) regulate proliferation, differentiation and apoptosis of target cells. Receptors for these cytokines consist of a cytokine-specific alpha subunit and a common shared beta c subunit.
P F, Dijkers +6 more
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