Results 91 to 100 of about 1,358,257 (368)

A map of human circular RNAs in clinically relevant tissues

Journal of molecular medicine, 2017
Cellular circular RNAs (circRNAs) are generated by head-to-tail splicing and are present in all multicellular organisms studied so far. Recently, circRNAs have emerged as a large class of RNA which can function as post-transcriptional regulators.
P. Maass, Petar Glažar, Sebastian Memczak, G. Dittmar, Irene Hollfinger, Luisa Schreyer, A. V. Sauer, O. Toka, A. Aiuti, F. Luft, N. Rajewsky   +10 more
semanticscholar   +1 more source

A road map to Translational Medicine in Qatar and a model for the world [PDF]

Journal of Translational Medicine, 2012
Translational Medicine (TM) in Qatar is part of a concerted effort of the Qatari medical and scientific leadership supported by a strong political will by Qatari authorities to deliver world-class health care to Qatari residents while participating in the worldwide quest to bridge the gap between bench-to-bedside-to-community.
Javaid I. Sheikh, Francesco M Marincola, Francesco M Marincola   +2 more
openaire   +4 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Experiences of participating in a group-based sensory modulation intervention for mental health service users

Scandinavian Journal of Occupational Therapy
Background People with mental health issues often experience difficulties with sensory modulation affecting occupational engagement. Research conducted in inpatient units has shown positive effects of individual sensory modulation interventions, however,
Klara Forsberg, Daniel Sutton, Sigrid Stjernswärd, Ulrika Bejerholm, Elisabeth Argentzell   +4 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Adaptive data-driven age and patch mixing in contact networks with recurrent mobility

MethodsX, 2022
Infectious disease transmission models often stratify populations by age and geographic patches. Contact patterns between age groups and patches are key parameters in such models. Arenas et al.
Jesse Knight, Huiting Ma, Amir Ghasemi, Mackenzie Hamilton, Kevin Brown, Sharmistha Mishra   +5 more
doaj  

Consensus on precision medicine for metastatic cancers: a report from the MAP conference.

Annals of Oncology, 2016
Recent advances in biotechnologies have led to the development of multiplex genomic and proteomic analyses for clinical use. Nevertheless, guidelines are currently lacking to determine which molecular assays should be implemented in metastatic cancers ...
C. Swanton, J. Soria, A. Bardelli, A. Biankin, C. Caldas, S. Chandarlapaty, L. de Koning, C. Dive, J. Feunteun, S. Leung, R. Marais, E. Mardis, N. Mcgranahan, G. Middleton, S. Quezada, J. Rodón, N. Rosenfeld, C. Sotiriou, F. André   +18 more
semanticscholar   +1 more source

Cartographies of Disease: Maps, Mapping, and Medicine (New Expanded Edition) [PDF]

The AAG Review of Books, 2018
Tom Koch. Redlands, CA: ESRI Press, 2017. xxi and 403 pp., maps, illustrations, notes, bibliography, index.
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Getting Histoplasmosis on the Map of International Recommendations for Patients with Advanced HIV Disease

Journal of Fungi, 2019
Progressive disseminated histoplasmosis, caused by H. capsulatum, is a life-threatening illness and is an AIDS-defining opportunistic infection. It is neglected, worryingly under-diagnosed, and often misdiagnosed as cancer or tuberculosis with fatal ...
F. Bongomin, Richard Kwizera, D. Denning
semanticscholar   +1 more source