Results 101 to 110 of about 632,968 (345)

Understanding the role and organization of health workers delivering non-communicable disease management in primary care in low- and middle-income countries: a scoping review

BMC Primary Care
Background Non-communicable diseases are responsible for three-fourths of annual deaths worldwide and disproportionately affect individuals living in low- and middle-income countries.
Archna Gupta, Oluwasegun J. Ogundele, Roxana Rabet, Iryna Artyukh, Thiago Trindade, Doret Cheng, Daniel Osafo Darko, Mai Eltigany, Alarcos Cieza, Becky Skidmore, Katherine D. Rouleau   +10 more
doaj   +1 more source

Mistaking the Map for the Territory: What Society Does With Medicine

International Journal of Health Policy and Management, 2017
Van Dijk et al describe how society’s influence on medicine drives both medicalisation and overdiagnosis, and allege that a major political and ethical concern regarding our increasingly interpreting the world through a biomedical lens is that it serves ...
A. Wardrope
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Uptake of COVID-19 vaccination among community-dwelling individuals receiving healthcare for substance use disorder and major mental illness: a matched retrospective cohort study

Frontiers in Public Health
IntroductionPatients with major mental illness (MMI) and substance use disorders (SUD) face barriers in accessing healthcare. In this population-based retrospective cohort study, we investigated the uptake of COVID-19 vaccination in Ontario, Canada among
Lucie Richard, Anna Holland, Vivian Aghanya, Michael A. Campitelli, Stephen W. Hwang, Stephen W. Hwang, Stephen W. Hwang   +6 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

ClinicalLINKS Project within DDSWQ Medicare Local

International Journal of Integrated Care, 2014
Shirley-Anne Lee Gardiner, Tiana Gurney
doaj   +3 more sources

Interventions in ambulatory healthcare settings to reduce social isolation among adults aged 18–64: a systematic review

BJGP Open
Background: Social isolation is associated with increased all-cause and premature mortality, poor chronic disease management, and mental health concerns.
Kavya Anchuri, Liane Steiner, Roxana Rabet, Amy Craig-Neil, Ellah San Antonio, Oluwasegun Jko Ogundele, Melanie Seabrook, Ceinwen Pope, Serina Dai, Andree Schuler, Carolyn Ziegler, Andrew David Pinto   +11 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source