Executive Summary: Knowledge Translation in Emergency Medicine: Establishing a Research Agenda and Guide Map for Evidence Uptake [PDF]
Eddy Lang, Peter Wyer, Barnet Eskin
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Health in Need of Healing: Church History as a Road Map for Future Evangelization in Medicine [PDF]
James O. Breen
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Efficacy of antimalarial herbal medicines used by communities in malaria affected regions globally: a protocol for systematic review and evidence and gap map [PDF]
Moses Ocan+5 more
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
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Medicine and Duty: The World War I Memoir of Captain Harold W. McGill, Medical Officer, 31st Battalion CEF. Edited by Marjorie Barron Norris. (Calgary: Calgary University Press, 2007. xxii + 379 p., ill., maps, tab., index. isbn 978-1-55238-193-9 $39.95) [PDF]
Andrew Iarocci
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Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
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Objectives: To analyze the scientific production of primary care research in Latin American and Caribbean (LAC) countries from 1980 to 2024 and to provide recommendations for improvement.
Muhammet Damar+2 more
doaj
Mapping of systematic reviews on traditional medicine across health conditions: a protocol for a systematic map [PDF]
Lin Ang+11 more
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Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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