Results 191 to 200 of about 655,074 (262)

Status of Evidence on the Efficacy and Safety of Indian Traditional Medicine for Prediabetes and Type 2 Diabetes Mellitus: Protocol for a Systematic Review and Evidence Map Synthesis. [PDF]

JMIR Res Protoc
Ruknuddin G, Ahmad A, S Gundeti M, R M, Wilson E, Itrat M, Javed G, Quamri MA, Singh Chalia D, Yadav P, T P A, K P K, C S A, H S M, Dileep A, Shetty P S.   +15 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Comparison of Volatile Anesthesia and Intravenous Anesthesia for Endovascular Thrombectomy in Acute Ischemic Stroke Patients Under General Anesthesia: A Systematic Review and Meta-Analysis. [PDF]

Crit Care Res Pract
Gois de Oliveira M, de Araujo W, de Oliveira LSG, Rodrigues LK, Barreto LAL, Dias YS, Pace N, Egan T.   +7 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A cascade model of dynamic cerebral autoregulation. [PDF]

J Physiol
Kurazumi T, Sharma K, Wennekers RRJ, Tomoto T, Cardim D, Won J, Ashley J, Claassen JAHR, Zhang R.   +8 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Implementation of the kidney protection strategy in critically ill patients with acute kidney injury - a multi-center prospective cohort study. [PDF]

Crit Care
Sadjadi M, Marcello M, Köhler A, Perschinka F, Schauflinger S, Joannidis M, Vadász I, Husain-Syed F, Klop-Riehl M, Pickkers P, Villa G, Nagel T, Bormann E, Booke H, Schöne LM, von Groote T, Mertes MJ, Kellum JA, Strauß C, Zarbock A.   +19 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Association of early mean arterial pressure trajectory subtypes with mortality in critically ill patients with ischemic stroke: A multicenter retrospective cohort study. [PDF]

Medicine (Baltimore)
Qiu J, Liu R.
europepmc   +1 more source

Trends and Research Hotspots in Biomarkers of Sjögren's Syndrome Over the Past Two Decades: A Data-Driven Atlas Analysis. [PDF]

Immun Inflamm Dis
Zhang X, Li H, Zhou X, Qi S, Li S.
europepmc   +1 more source