Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP-CARE): A protocol for a randomized clinical trial. [PDF]
Niemelä VH+77 more
europepmc +1 more source
Creation of novel training programmes mapped to the Joint Royal Colleges of Physicians Training Board Internal Medicine stage 1 curriculum [PDF]
Marie McNulty+9 more
openalex +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Association Between Visit-to-Visit Mean Arterial Pressure Variability and the Risk of Ischemic Heart Disease and Ischemic Stroke Among Patients With Hypertension in Thailand. [PDF]
Sakboonyarat B, Poovieng J, Rangsin R.
europepmc +1 more source
A Qualitative Study of Diversity in Precision Medicine Research: The Development and Stakeholder Assessment of a Diversity Decision Map [PDF]
Janet K. Shim+5 more
openalex +1 more source
Analyzing the use of linking words in concept maps designed for pathophysiology learning in medicine
Nuno Neuparth+11 more
openalex +2 more sources
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Oxidative Stress and Apoptotic Markers in Goats Naturally Infected with <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>. [PDF]
Ozturk M+7 more
europepmc +1 more source