How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Rising tides: Unveiling the spatial and temporal evolution of sea level rise under climate change. [PDF]
Liang B, Shi G, Zhu Y, Wu Y, Wang M.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Integrating Remote Sensing and Machine Learning to Project Global Habitat Suitability and Productivity of Chinese Fir Under Climate Change. [PDF]
Sun J +12 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Structural Origins of High MoO<sub>3</sub> Solubility in Peraluminous Borosilicate Glasses. [PDF]
Joseph NDI +6 more
europepmc +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Flex Projector - Interactive Program for Creating World Map Projections
Nedjeljko Frančula
doaj
CALPUCK: An Open Python Tool for Cremer-Pople Ring Puckering Analysis Including a New 2D Mapping of Seven-Membered Rings. [PDF]
Protti F, Toma L, Zanoni G, Casali E.
europepmc +1 more source
Climate Warming Will Reduce Boreal Forest Litterfall, but the Response Differs Among Plant Functional Types. [PDF]
Thu WP +4 more
europepmc +1 more source

