Results 41 to 50 of about 3,770,310 (253)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

La primera fiesta litúrgica de Nuestra Señora

Estudios Eclesiásticos, 1965
Las siguientes páginas recogen, discuten y clasifican los resultados obtenidos sobre la primera fiesta en honor a Nuestra Señora. Esto no equivale a señalar los principios de culto litúrgico mariano, ni tampoco de la veneración que el pueblo ha dedicado ...
José Antonio de Aldama
doaj  

Increased levels of hyaluronic acid in bronchoalveolar lavage from patients with interstitial lung diseases, relationship with lung function and inflammatory cells recruitment [PDF]

, 2014
Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It described the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contributes to the recruitment of inflammatory cells associated with ILD.
Auteri, Santiago, Ernst, Glenda, Galíndez, Fernando, Grynblat, Pedro, Hajos, Silvia Elvira, Jancic, Carolina Cristina, Rodriguez Moncalvo, Juan   +6 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Neurociencia y mercadeo: influencia del color en la predisposición de compra en usuarios de redes sociales

Revista de Iniciación Científica, 2020
En este trabajo se evalúa la predisposición de compra de productos genéricos y de marcas reconocidas con respecto al color predominante, utilizados en anuncios publicados en redes sociales.
Isabella Membreño, Briggitte Rodríguez, Loreli González, Ericka Castillero, Ricardo Cattafi   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

imagen corporal de la Santísima Virgen en la literatura antigua cristiana

Estudios Eclesiásticos, 1951
La imagen corporal de María es un tema de actualidad teológica desde la definición dogmática de la Asunción de Nuestra Señora. El contenido dogmático de este título consiste precisamente en que el cuerpo de María, con todas sus partes y sentidos, vive ...
Juan Leal
doaj  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Desinserción espontánea y bilateral del tendón cuadricipital.

Revista de la Asociación Argentina de Ortopedia y Traumatología, 2016
La ruptura espontánea bilateral del tendón cuadricipital es una patología infrecuente (
Jesuan Zordan, Federico Bacigalupo, Hernán Bustamante, Romina Candidori   +3 more
doaj   +1 more source

El río de la Memoria [PDF]

, 2009
Artistas participantes: José Cala Fontquernie, Frank-Joachim Grossmann, Karen Pullich, Alexander Pawlik, Andreina Scanu, Aiman HH, Ángeles de la Torre, Anna Jonnson, Arnaud Velten, David Toral, César Ripoll, Catherine Weber, Dieter Zurnieden, Elena Toral,
Algovi, Jesús
core