Correction: McCutchan, A.L.; Johnson, B.A. Laboratory Experiments on Ice Melting: A Need for Understanding Dynamics at the Ice-Water Interface. J. Mar. Sci. Eng. 2022, 10, 1008 [PDF]
Aubrey Lynn McCutchan, Blair Johnson
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Mar à vista: espaço transitivo no tempo diagonal bogeano
Em 10 de setembro deste ano, tive o privilégio de conhecer a arquitetura projetada por Marta Bogéa para abrigar a 29a Bienal de Artes de São Paulo, passeando, na companhia da própria, pelo singular e turbulento canteiro de obras da intervenção ...
Myrna de Arruda Nascimento
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Calcic melt inclusions in primitive olivine at 43°N MAR: evidence for melt–rock reaction/melting involving clinopyroxene-rich lithologies during MORB generation [PDF]
Vadim S. Kamenetsky +5 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Enrichment of Aerobic and Anaerobic Hydrocarbon-Degrading Bacteria from Multicontaminated Marine Sediment in Mar Piccolo Site (Taranto, Italy) [PDF]
Bruna Matturro +7 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Das Logatchev Hydrothermalfeld (MAR, 15°N): Hoch- und Niedrigtemperaturalteration von ultramafischer ozeanischer Kruste ; Geologie, Geochemie, Mineralogie [PDF]
Augustin, Nico
openalex

