Results 131 to 140 of about 294 (212)

Discovery of a cryptic aminoacidic triad involved in the temperature adaptation of GH1 enzymes

The FEBS Journal, EarlyView.
Cold‐active enzymes retain high catalytic activity at low temperatures but are characterized by thermal instability, a behavior not fully understood. Comparison between a cold‐active GH1 and its mesophilic counterparts highlights the role of a three‐residue motif (W‐M‐F) in conferring structural stability to a mesophilic GH1.
Stefania Digiovanni, Gabriel Oanca, Marco Orlando, Marina Lotti, Johan Åqvist, Marco Mangiagalli   +5 more
wiley   +1 more source

Composición y distribución espacial de la fauna bentónica del LIC "Acantilados y Fondos Marinos de Calahonda - Castell de Ferro" (Mar de Alborán)

, 2012
0
Marina-Ureña, P. (Pablo), Rueda, J.L. (José Luis), Baro, J. (Jorge), García-Jiménez, M.T. (María Teresa), Salas, C., Gofas, S. (Serge), García-Raso, J.E. (José Enrique), López-González, N. (Nieves), Moya-Ruiz, F. (Francisca), Laiz-Carrión, R. (Raúl)   +9 more
openaire   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Recompression Improves Release Success in Pollack (Pollachius pollachius): A Step Towards Assessing Post Release Mortality in a Recreational Fishery

Fisheries Management and Ecology, EarlyView.
ABSTRACT The recreational fishery for pollack (Pollachius pollachius) in the northeast Atlantic is impacted by the species' high sensitivity to barotrauma. When captured at depth and brought to the surface, gas expansion within the peritoneal cavity can cause a variety of injuries and hinder release.
T. Stamp, R. Mawer, R. Conlon, A. E. Hall, P. Davies, R. Nesbit, D. Uren, T. Morris, S. Sullivan, S. Thomas, B. D. Stewart, H. Rudd, K. Hyder, T. Osmond, S. Reynell, E. V. Sheehan   +15 more
wiley   +1 more source

Do people with HIV really have the choice between oral and injectable ART? Evidence from a multicentric survey in the Swiss HIV cohort study

HIV Medicine, EarlyView.
Abstract Introduction Injectable long‐acting antiretroviral therapy (iLA‐ART) offers a valuable alternative to oral ART (oART). While the efficacy of these treatment strategies is similar, adequate information on their specific characteristics is essential to enable people with HIV (PWH) to decide which option best suits their values and preferences ...
Yonas Martin, Bernard Surial, Martin Müller, Lukas Baumann, David Jackson‐Perry, David Haerry, Marie Ballif, Charles Béguelin, Miriam Bürgi, Aline Munting, Matthias Cavassini, Dominique Braun, Andri Rauch, Reto Auer, Gilles Wandeler, the Swiss HIV Cohort Study   +15 more
wiley   +1 more source

CHildren of the Cohort Study (CHOC): Exploring parenting desire among people living with HIV in Switzerland

HIV Medicine, EarlyView.
Abstract Background Although HIV is now a chronic condition with an excellent life expectancy, some personal aspects affecting people living with HIV (PLWH), such as parenting desire, are relatively understudied. This study aimed to explore parenting desire among PLWH in Switzerland.
Clara Merlin, José Damas, Olivier Nawej Tshikung, Noémie Wagner, Anna Hachfeld, Andrea Duppenthaler, Marcel Stoeckle, Malte Kohns, Irene A. Abela, Paolo Paioni, Luigia Elzi, Lisa Kottanattu, Patrick Schmid, Christian R. Kahlert, Katharina Kusejko, Pierre Alex Crisinel, Pascal Pellegrino, Matthias Cavassini, Katharine E. A. Darling, the Swiss HIV Cohort Study, IA Abela, K Aebi‐Popp, A Anagnostopoulos, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, JS Fehr, J Fellay, S Frigerio Malossa, CA Fux, HF Günthard, A Hachfeld, DHU Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, CR Kahlert, D Kaufmann, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, ND Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, Child Substudy, G Pantaleo, M Perreau, A Rauch, LP Salazar‐Vizcaya, P Schmid, O Segeral, RF Speck, M Stöckle, B Surial, PE Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +76 more
wiley   +1 more source

Caracterización de la basura marina del fondo del mar en el Mediterráneo español a través de la pesca de arrastre

, 2019
La presente tesis por compendio de publicaciones se apoya en dos artículos publicados en la revista Marine Pollution Bulletin. En el primer trabajo se da una visión general del estado de la basura marina depositada sobre el lecho marino en la costa mediterránea de la Península Ibérica.
openaire   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

Propuesta participativa de acciones de prevención en zonas afectadas por inundaciones fluviales y mar de fondo, en Coyuca de Benítez, Guerrero.

, 2018
This work proposes actions of prevention in case of fluvial floods and swell, in a participative way, between the communities and local authorities, in two demarcations of the municipality of Coyuca de Benitez: the Locality of the Barra and the Zumpango Colony, which historically they have suffered severe damages in their economy and in their integrity
openaire   +1 more source

Jorge Luis Borges' Medieval Aesthetics of Failure

Critical Quarterly, EarlyView.
Irina Dumitrescu
wiley   +1 more source