Results 21 to 30 of about 180,426 (259)

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control

BMC Medicine, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian, W. J. Edmunds, Daniel G. Bausch, T. Jombart   +3 more
semanticscholar   +1 more source

The mortality, modes of infection, diagnostic tests, and treatments of Marburg virus disease: A systematic review

Health Science Reports, 2023
Marburg virus (MARV) has regularly affected people since 1967 causing multiple outbreaks. There are presently no authorized therapies for the fatal Marburg virus disease (MVD), which poses an imminent risk to global public health.
Deekshitha Alla, Sai Sri Hari Paruchuri, Angad Tiwari, Sai Santhosha Mrudula Alla, Rakesh Thulaseedharan Pillai, Sandeep Kumar Reddy Bandakadi, Anju Pradeep, D. J. Shah, Mert Sabıroğlu, Sachi Chavda, Patrick Biziyaremye   +10 more
semanticscholar   +1 more source

Micro‒Global Positioning Systems for Identifying Nightly Opportunities for Marburg Virus Spillover to Humans by Egyptian Rousette Bats

Emerging Infectious Diseases, 2023
Marburg virus disease, caused by Marburg and Ravn orthomarburgviruses, emerges sporadically in sub-Saharan Africa and is often fatal in humans. The natural reservoir is the Egyptian rousette bat (ERB), which sheds virus in saliva, urine, and feces ...
Brian R. Amman, Amy J. Schuh, Gloria Akurut, Kilama Kamugisha, Dianah Namanya, Tara K. Sealy, James C. Graziano, Eric Enyel, Emily A. Wright, Stephen Balinandi, Julius J. Lutwama, Rebekah C. Kading, Patrick Atimnedi, Jonathan S. Towner   +13 more
doaj   +1 more source

Marburg virus disease treatments and vaccines: recent gaps and implications

Annals of Medicine and Surgery, 2023
Marburg virus disease (MVD), caused by the Marburg virus (MARV) of the Filoviridae ...
Khaled Albakri, Momen Al-Hajali, O. Saleh, Ayah M. Alkhalil, Ahmed B. Mohd, Carla A. Samain, Nadeen N. Abuasad, Hanan Hasan, Abdurthman Khaity, R. Farahat   +9 more
semanticscholar   +1 more source

Rise of Marburg virus in Africa: a call for global preparedness

Annals of Medicine and Surgery, 2023
The Marburg virus disease (MVD) is caused by a rare RNA virus that can result in severe hemorrhagic fever in humans and other primates. The disease was first discovered in 1967 in Marburg Frankfurt in Germany and since then, sporadic cases have been ...
O. Okesanya, E. Manirambona, N. O. Olaleke, H. A. Osumanu, A. A. Faniyi, O. Bouaddi, Olatunji Gbolahan, Jose J. Lasala, D. Lucero‐Prisno   +8 more
semanticscholar   +1 more source

A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

bioRxiv, 2022
Background Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West Africa for the first time.
Courtney Woolsey, R. Cross, K. Agans, V. Borisevich, D. Deer, J. Geisbert, Cheryl S. Gerardi, Theresa Latham, Karla A. Fenton, M. Egan, J. Eldridge, T. Geisbert, Demetrius Matassov   +12 more
semanticscholar   +1 more source

Marburg virus disease: A deadly rare virus is coming.

BioScience Trends, 2022
Two cases of the deadly Marburgvirus were reported in Ghana, which might be a new global virus alert following COVID-19 and novel monkeypox. Thus far, there is no vaccine or treatment for Marburg virus disease, which is a disease with a mortality rate as
Fang Zhao, Yun He, Hongzhou Lu
semanticscholar   +1 more source

An introduction to the Marburg virus vaccine consortium, MARVAC

PLoS Pathogens, 2022
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectious ...
R. Cross, I. Longini, S. Becker, K. Bok, David Boucher, M. Carroll, Janet Diaz, W. Dowling, R. Draghia‐Akli, J. T. Duworko, J. Dye, M. Egan, P. Fast, Amy Finan, Courtney L. Finch, T. Fleming, J. Fusco, T. Geisbert, Anthony Griffiths, S. Günther, L. Hensley, A. Honko, Ruth Hunegnaw, J. Jakubik, J. Ledgerwood, K. Luhn, Demetrius Matassov, J. Meshulam, E. Nelson, C. Parks, R. Rustomjee, D. Safronetz, L. Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, C. Spiropoulou, N. Sullivan, Kelly L. Warfield, Daniel Wolfe, Courtney Woolsey, R. Zahn, A. Henao-Restrepo, C. Muñoz-Fontela, A. Marzi   +44 more
semanticscholar   +1 more source

Case Report: Successful Stabilization of Marburg Variant Multiple Sclerosis With Ocrelizumab Following High-Dose Cyclophosphamide Rescue

Frontiers in Neurology, 2021
The Marburg variant of multiple sclerosis (Marburg MS) is the most aggressive form of MS, often leading to death soon after onset. Here we describe the case of a 26-year-old Marburg MS patient presenting with severe neurological deficits requiring ...
Valeria Koska, Moritz Förster, Katja Brouzou, Maryam Hatami, Ercan Arat, Ahmet Aytulun, Philipp Albrecht, Orhan Aktas, Patrick Küry, Sven G. Meuth, David Kremer   +10 more
doaj   +1 more source

Marburg Virus Disease – A Mini-Review

Journal of Experimental Biology and Agricultural Sciences, 2022
Marburg virus disease (MVD) is a highly fatal disease caused by the Marburg virus (MARV) which belongs to the family Filoviridae. The disease has been recently reported from Ghana, an African country, and nearly 15 outbreaks of MVD have been reported in ...
Sandip Chakraborty, Deepak Chandran, R. Mohapatra, M. Alagawany, M. I. Yatoo, Md. Aminul Islam, A. Sharma, K. Dhama   +7 more
semanticscholar   +1 more source