Results 11 to 20 of about 849,516 (245)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
MARC 21 формат для бібліографічних даних
, 2021 У виданні надано методичні рекомендації щодо застосування формату MARC 21 для бібліографічних даних для створення бібліографічних записів в електронних каталогах бібліотек. Рекомендації складено з урахуванням міжнародного стандарту каталогізації в цифровому середовищі RDA – Опис та доступ до ресурсів (Resource Description & Access).
openaire +1 more source
Ohjeet yhteisön kuvailutietojen merkitsemiseksi Fennican auktoriteettitietokantaan Marc 21-formaatissa [PDF]
, 2013 Tässä ohjeessa esitellään lyhyesti yhteisöauktoriteettitietueen laadintaan liittyviä tavallisimmin tarpeellisia sääntöjä ja formaatin ...
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Software system for MARC 21 cataloguing [PDF]
, 2013 Извршено је моделирање и имплементација софтверског система за каталогизацију по MARC 21 формату. За реализацију система коришћен је обједињени процес за развој софтвера, развој заснован на моделу и развој заснован на софтверским компонентама. Моделирање је извршено у CASE алату 235 MagicDraw верзија 16.0 који подржава UML
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Conversão de registro MARC 21 para Dublin Core na Agência de Informação Embrapa. [PDF]
, 2011 bitstream/CNPTIA/11543/1/ct80.pdfAcesso em: 28 maio ...
ALVES, M. das D. R., SOUZA, M. I. F.
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source