Results 21 to 30 of about 4,862,841 (293)

Metapodatkovni standardi za opis građe Kongresne knjižnice

open access: yesLibellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2023
Cilj. Cilj je rada prikaz razvoja metapodatkovnih standarda za opis građe – ili shema metapodataka – Kongresne knjižnice u Washingtonu, SAD, iniciranog ubrzanim razvojem tehnologije i rasta mrežnog okruženja u posljednjim desetljećima.
Bernarda Bošnjak, Boris Bosančić
doaj   +1 more source

Representação no domínio bibliográfico: um olhar sobre os Formatos MARC 21

open access: yesPerspectivas em Ciência da Informação
Resumo: A representação da informação tem sido realizada em diversos domínios, um deles o domínio bibliográfico, onde está pautada em instrumentos, princípios, modelos e tecnologias, tais como os padrões de metadados e as codificações.
Fabrício Silva Assumpção   +1 more
doaj   +1 more source

MARC 21 para recursos contínuos [PDF]

open access: yes, 2011
Translation and adaptation of the MARC 21 Format for Bibliographic Data, and MARC 21 Format for Holdings Data, Network Development and MARC Standards Office, Library of Congress, USA, by Angela Salles. Rio de Janeiro, 2010. 2 v.
Salles, Angela
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

MARC zapisi i XML = Marc records and XML [PDF]

open access: yes, 2004
This article describes how a MARC record has evolved in the decades since its introduction, i.e. from the ISO 2709 to XML format. The XML format is a general format for presenting MARC records in a simple and understandable way.
Budimir, Gordana
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

MARC 21 формат для бібліографічних даних

open access: yes, 2021
У виданні надано методичні рекомендації щодо застосування формату MARC 21 для бібліографічних даних для створення бібліографічних записів в електронних каталогах бібліотек. Рекомендації складено з урахуванням міжнародного стандарту каталогізації в цифровому середовищі RDA – Опис та доступ до ресурсів (Resource Description & Access).
openaire   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

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