Results 61 to 70 of about 16,781,830 (337)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Effect of Interrow Spacings on Growth, Yield, and Yield Components of Common Bean (Phaseolus vulgaris L.) Varieties in the Central Rift Valley of Ethiopia

open access: yesAdvances in Agriculture, 2023
The common bean is the crop used as food, feed, and to improve soil fertility. However, the production and productivity were affected by poor nutrition and fertilizer management, inappropriate interrow spacings, and the poor genetic makeup of the crops ...
Shanko Bakure   +2 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

From MARC silos to Linked Data silos?

open access: yeso-bib. Das offene Bibliotheksjournal, 2017
Libraries are opening up their bibliographic metadata as Linked Data. However, they have all used different data models for structuring their bibliographic data.
Osma Suominen, Nina Hyvönen
doaj   +1 more source

Extraction of Anthocyanins from Grape ( Vitis Vinifera ) Skins Employing Natural Deep Eutectic Solvents (nades)

open access: yesChemical Engineering Transactions, 2021
In the last years, the possibility to exploit the high added value bioactive compounds obtained by the solid residues of the winemaking process in cosmetic, food supply and pharmaceutical field was explored.
Annalaura Iannone   +4 more
doaj   +1 more source

By-Products from Winemaking and Olive Mill Value Chains for the Enrichment of Refined Olive Oil: Technological Challenges and Nutraceutical Features

open access: yesFoods, 2020
A growing body of literature is available about the valorization of food by-products to produce functional foods that combine the basic nutritional impact with the improvement of the health status of consumers.
Monica Macaluso   +13 more
doaj   +1 more source

Half-Duplex Relaying for the Multiuser Channel

open access: yes, 2014
This work focuses on studying the half-duplex (HD) relaying in the Multiple Access Relay Channel (MARC) and the Compound Multiple Access Channel with a Relay (cMACr).
Lei, Ming, Soleymani, Mohammad Reza
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway

open access: yesVirology Journal, 2018
Porcine reproductive and respiratory syndrome virus(PRRSV) is an important immunosuppressive virus which can suppresses infected cells proliferation.
Linlin Song   +9 more
doaj   +1 more source

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