Results 11 to 20 of about 188,388 (150)

Long‐term prevention of bladder cancer progression by alpha1‐oleate alone or in combination with chemotherapy

open access: yesInternational Journal of Cancer, Volume 153, Issue 3, Page 584-599, 1 August 2023., 2023
What's new? The tumoricidal complex alpha1‐oleate is active as a bladder cancer therapeutic and has shown efficacy in patients without evidence of toxicity. Here, the authors tested whether repeated treatment with alpha1‐oleate, combined with low‐dose chemotherapy, would improve long‐term treatment efficacy.
Tran Thi Hien   +8 more
wiley   +1 more source

Nanostructured Lipid Carriers for Improved Delivery of Therapeutics via the Oral Route

open access: yesJournal of Nanotechnology, Volume 2023, Issue 1, 2023., 2023
Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the primary hiccups for effective oral delivery of medications. With the advent of nanotechnology, nanostructured lipid carriers (NLCs) have emerged as a promising delivery carrier ...
Alok Kumar Mahor   +11 more
wiley   +1 more source

Law‐books, concomitant texts and ethnically framed legal pluralism on the fringes of post‐Carolingian Europe: northern Italy and Catalonia around 1000

open access: yesEarly Medieval Europe, Volume 30, Issue 4, Page 536-557, November 2022., 2022
Around 1000, a new type of law‐book emerged in Catalonia and northern Italy that attests to new ways of handling legal material. Incorporating in full the Visigothic and Lombard law codes, respectively, these law‐books provided a base for studying and interpreting old law through comments, glosses etc., addressing new users such as lay judges.
Stefan Esders
wiley   +1 more source

Gut tissue‐resident memory T cells in coeliac disease

open access: yesScandinavian Journal of Immunology, Volume 95, Issue 1, January 2022., 2022
Abstract This mini‐review describes observations of the 1990ies with culturing of gluten‐specific and astrovirus‐specific CD4+ T cells from duodenal biopsies from subjects who presumably had a long time between the exposure to gluten or astrovirus antigens and the sampling of the biopsy. In these studies, it was also observed that antigen‐specific CD4+
Ludvig M. Sollid
wiley   +1 more source

Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver

open access: yesEuropean Journal of Immunology, Volume 51, Issue 11, Page 2568-2575, November 2021., 2021
Di Censo et al. identified distinct ILC1 populations in the mouse liver, defined by the expression of granzyme A (GzmA) and CD160. Expression of these molecules is finely tuned perinatally and delineates ILC1 with graded ability to produce IFN‐γ and to kill cancer cells.
Chiara Di Censo   +27 more
wiley   +1 more source

Know your enemy or find your friend?—Induction of IgA at mucosal surfaces

open access: yesImmunological Reviews, Volume 303, Issue 1, Page 83-102, September 2021., 2021
Abstract Most antibodies produced in the body are of the IgA class. The dominant cell population producing them are plasma cells within the lamina propria of the gastrointestinal tract, but many IgA‐producing cells are also found in the airways, within mammary tissues, the urogenital tract and inside the bone marrow. Most IgA antibodies are transported
Mats Bemark, Davide Angeletti
wiley   +1 more source

The limits of Quediini at last (Staphylinidae: Staphylininae): a rove beetle mega‐radiation resolved by comprehensive sampling and anchored phylogenomics

open access: yesSystematic Entomology, Volume 46, Issue 2, Page 396-421, April 2021., 2021
Novel probe set developed for anchored hybrid enrichment of Staphylinidae (Coleoptera), targeting 1229 single‐copy, protein‐encoding, orthologous loci from the nuclear genome. Comprehensive phylogeny of rove beetle tribe Quediini (∼800 spp.), with 46% of 201 ingroup taxa sequenced from pinned specimens, will serve as framework for needed generic ...
Adam J. Brunke   +15 more
wiley   +1 more source

Uma análise dos principais elementos influenciadores da tomada de decisão de compra de produtos de marca própria de supermercados

open access: yes, 2012
The adoption of own brands in the product mix of supermarkets is a strategic action that some retailers are using to improve their competitiveness in the sector.
Lucía Silva, E. Merlo, M. S. Nagano
semanticscholar   +1 more source

Compact portable multiphoton microscopy reveals histopathological hallmarks of unprocessed lung tumor tissue in real time

open access: yesTranslational Biophotonics, Volume 2, Issue 4, November 2020., 2020
A portable label‐free real‐time ex‐vivo microscope is used to investigate fresh unprocessed lung tumor tissue by generating third harmonic generation (THG), second harmonic generation (THG) and two‐photon excited fluorescence (2PEF) images, and comparing those images with standard HE histology images.
Laura M. G. van Huizen   +8 more
wiley   +1 more source

The scabini in historiographical perspective

open access: yesHistory Compass, Volume 18, Issue 10, October 2020., 2020
Abstract The introduction of the scabini, men who served as judgement finders, has long been connected to judicial reform enacted by Charlemagne. By the thirteenth century, the term scabini had become synonymous with legal culture and courts from Norway to Hungary and beyond. This article will trace the scabini from historiographical debates over their
Alice Hicklin
wiley   +1 more source

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