Results 91 to 100 of about 35,038 (256)

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Moyamoya Disease in an Eight‐Year‐Old Female Child—A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT An eight‐year‐old girl presented with a first episode of focal seizure and transient loss of consciousness. Brain MRI revealed a large subacute infarct in the left fronto‐parieto‐temporal region, and MR angiography showed bilateral supraclinoid internal carotid and proximal posterior cerebral artery narrowing with extensive basal collateral ...
Disha Thapa, Sai Priya Nimmagadda, Betsy Annie Philip, Shreya Milind Kawade, Abhisar Rohila, Mihirkumar P. Parmar, Saleh Mohammed   +6 more
wiley   +1 more source

Management of Marfan Syndrome, with a Specific Focus on the Significance of Physical Activity in this Patient Population

Quality in Sport
Introduction: Marfan syndrome is an autosomal dominant disorder of connective tissue. Timely diagnosis and effective therapy are essential for individuals with Marfan syndrome, as they are susceptible to severe cardiovascular consequences, including ...
Patrycja Jędrzejewska-Rzezak
doaj   +1 more source

THE CONDITION OF DISTAL AORTA AFTER PROXIMAL RECONSTRUCTION FOR DISSECTION IN MARFAN SYNDROME

Российский кардиологический журнал, 2016
Marfan syndrome is a disease associated with high prevalence of aorta-related morbidity and mortality. Dissections and ruptures of thoracal aorta (ThAo) lead to decreased life duration in persons with Marfan syndrome with mediana at 30 year-old.Aim.
A. M. Chernyavskiy, M. M. Lyashenko, D. A. Sirota, S. A. Alsov, D. S. Khvan   +4 more
doaj   +1 more source

Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome. [PDF]

, 2018
Objective: Marfan syndrome (MS) is a multisystem disorder caused by a mutation in FBN1 gene. It shares some phenotypic features with hypermobile Ehlers-Danlos syndrome (EDS) such as joint hypermobility.
Child, A, Hayat, JO, Inayet, N, Kaul, A, Poullis, A, Tome, M   +5 more
core   +1 more source

Post‐Traumatic Pseudoaneurysm of the Ulnar Artery: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Pseudoaneurysm of the ulnar artery is a rare condition with limited cases reported in the literature. It can be a medical emergency requiring prompt diagnosis and management to avoid life‐threatening complications. Here, we present a case of ulnar artery pseudoaneurysm, detailing its diagnosis through radiological imaging and subsequent ...
Omama Subul Islam, Hamza Ehtesham, Mushtaq Ahmad, Marium Omair Mirza, Ali Raza, Imran Ahmed Khan, Mahfuza Anan   +6 more
wiley   +1 more source

DNA methylation ambiguity in the Fibrillin-1 (FBN1) CpG island shore possibly involved in Marfan syndrome [PDF]

, 2020
Yoshikazu Arai, Kazuhiro Umeyama, Natsumi Okazaki, Kazuaki Nakano, Koichiro Nishino, Hiroshi Nagashima, Jun Ohgane   +6 more
openalex   +1 more source

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease [PDF]

, 2009
The events that convert adherent epithelial cells into individual migratory cells that can invade the extracellular matrix are known collectively as epithelial-mesenchymal transition (EMT).
Akitaya, Alkhateeb, Andersson, Barrallo-Gimeno, Bertocchini, Chea, Ciruna, del Barrio, Dixon, Dottori, el Ghouzzi, Favier, Gans, Garcia-Castro, Giehl, Haraguchi, Hervé Acloque, Iwano, Johansson, Kalluri, Katherine Fishwick, Kitajima, Kos, Kwok, Liu, Liu, M. Angela Nieto, Manzanares, Marianne Bronner-Fraser, Martin, Mathieu, Meghan S. Adams, Moreno-Bueno, Nakagawa, Nakaya, Nieto, Peinado, Perea-Gomez, Perez-Pomares, Pijnenborg, Popperl, Sato, Sela-Donenfeld, Sela-Donenfeld, Selleck, Shah, Skromne, Tanimizu, Thiery, Varlet   +49 more
core   +3 more sources

Transforming Growth Factor‐β‐Mediated Fibrotic Remodeling Drives Chronic Kidney Disease in Methylmalonic Aciduria and Propionic Aciduria—Identification of a New Therapeutic Target

Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Propionic aciduria (PA‐uria) and methylmalonic aciduria (MMA‐uria) are caused by defects in propionate catabolism. While chronic kidney disease (CKD) is a well‐established complication in MMA‐uria, renal involvement in PA‐uria has only come into focus more recently, and the underlying mechanisms remain poorly understood.
Karina A. Zeyer, Stefan Tholen, Oliver Schilling, Leonie Gerling, Marina Morath, Stefan Kölker, Alexander Nyström, Ute Spiekerkoetter, Anke Schumann   +8 more
wiley   +1 more source