Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]
, 2020 Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark +2 more
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Bentall procedure: quarter century of clinical experiences of a single surgeon [PDF]
, 2016 BACKGROUND: We retrospectively analyzed 25 years of experiences with the button Bentall procedure in patients with aortic root pathologies. Even though this procedure has become widespread, there are only a few very long term follow-ups available in the ...
Agg B +10 more
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Cardiovascular genetic counselor decision making about discussing life insurance with patients
Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.Abstract Genetic counselors (GCs) educate patients about the benefits, risks, and limitations of genetic testing. The regulatory environment governing the use of genetic data in life insurance is not uniform internationally or within the United States (US).
Sara Cherny +4 more
wiley +1 more source
Induction of macrophage chemotaxis by aortic extracts from patients with Marfan syndrome is related to elastin binding protein. [PDF]
PLoS ONE, 2011 Marfan syndrome is an autosomal dominantly inherited disorder of connective tissue with prominent skeletal, ocular, and cardiovascular manifestations. Aortic aneurysm and dissection are the major determinants of premature death in untreated patients.
Gao Guo +6 more
doaj +1 more source
, 2020 Arterial tortuosity syndrome (ATS) is a recessively inherited connective tissue disorder, mainly characterized by tortuosity and aneurysm formation of the major arteries.
Barnhoorn, Sander +14 more
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Abraham Lincoln, Aortic Regurgitation and Abscesses [PDF]
, 2014 Abraham Lincoln was an exceptionally tall man with a long, thin face and huge hands and feet. His mother had a similar build – an observation that in 1962 led AM Gordon to first propose that President Lincoln had Marfan ...
Bhatia, Sunil +4 more
core +1 more source
Characterisation of spinal ligaments in the embryonic chick
Journal of Anatomy, Volume 247, Issue 6, Page 1174-1186, December 2025.Use of the embryonic chick provides an opportunity to examine the maturation of spinal ligaments during development, to inform anatomical defects in the spine. Abstract Ligaments are important connective tissues within the musculoskeletal system that connect bone to bone and provide support and stability.
Sarah Hennigan +2 more
wiley +1 more source
Serial clinical and echocardiographic evaluation in children with Marfan syndrome [PDF]
, 2005 OBJECTIVE: To describe the clinical cardiac manifestations and temporal evolution of Marfan syndrome in children; to estimate the incidence of annuloaortic ectasia and mitral valve prolapse; and to evaluate tolerability and efficacy of beta-blockers in ...
Campos Filho, Orlando +7 more
core +5 more sources
Fibers and Polyphenols in Diverticular Disease: From Pathophysiology to Management
Neurogastroenterology &Motility, Volume 37, Issue 12, December 2025.ABSTRACT Backgrounds Diverticular disease, particularly symptomatic uncomplicated diverticular disease (SUDD), significantly impacts patient quality of life and is increasing in prevalence, especially in Western countries. While its pathophysiology is multifactorial, diet—specifically low fiber intake—has been implicated as a key modifiable factor in ...
Claudia Marinaccio +8 more
wiley +1 more source
Intrascleral four-flanged intraocular lens fixation technique for lens dislocation with Marfan syndrome [PDF]
, 2022 Li Zhou, Yong Wang
openalex +1 more source