Results 21 to 30 of about 899,001 (251)

A dietary-wide association study (DWAS) of environmental metal exposure in US children and adults. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:A growing body of evidence suggests that exposure to toxic metals occurs through diet but few studies have comprehensively examined dietary sources of exposure in US populations. PURPOSE:Our goal was to perform a novel dietary-wide association
Matthew A Davis   +6 more
doaj   +1 more source

Building the Evidence Base for the Prevention of Raw Milk-Acquired Brucellosis: A Systematic Review

open access: yesFrontiers in Public Health, 2020
Background: The scientific evidence of the health risks associated with the consumption of raw milk has been known for a long time. However, less clear is the impact of acquiring infectious diseases from raw milk consumption in the United States (US) due
Shakirat A. Adetunji   +5 more
doaj   +1 more source

Toward a Genealogy of Social Epistemology: Conceptual Origins and Re-invention of the Research Field

open access: yesSententiae
This article presents a historical-philosophical study of the formation of social epistemology as a distinct field. The author identifies two stages in its development: the initial conceptualization in 1950s library science (the project of Margaret Egan ...
Stefaniia Sidorova
doaj   +1 more source

Are international organizations agents in their own right? A plural subject perspective

open access: yesInternational Theory
The paper advances a novel theoretical perspective on the agency of international organizations (IOs). It argues that existing accounts–whether focused on intraorganizational actors such as bureaucracies or on member-dominated IOs–overlook the fact that ...
Jelena Cupać
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

An olfactory demography of a diverse metropolitan population

open access: yesBMC Neuroscience, 2012
Background Human perception of the odour environment is highly variable. People vary both in their general olfactory acuity as well as in if and how they perceive specific odours.
Keller Andreas   +4 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

open access: yesArthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram   +25 more
wiley   +1 more source

The World of Gilbert and George

open access: yes, 1981
Credits. Christ Church, Spitalfields, London; 360° view of London skyline. Gilbert, George. Rooftops: George Passmore’s VO recites "Misery for all.

core   +4 more sources

The taxonomic and functional diversity of microbes at a temperate coastal site: a 'multi-omic' study of seasonal and diel temporal variation. [PDF]

open access: yesPLoS ONE, 2010
How microbial communities change over time in response to the environment is poorly understood. Previously a six-year time series of 16S rRNA V6 data from the Western English Channel demonstrated robust seasonal structure within the bacterial community ...
Jack A Gilbert   +11 more
doaj   +1 more source

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