Results 51 to 60 of about 214,968 (299)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Biomass, Seed and Energy Yield of Cynara cardunculus L. as Affected by Environment and Season
Agronomy, 2020 Cynara cardunculus is a perennial plant that adapts well to Mediterranean climate conditions. The possibility of cultivating C. cardunculus with low or zero input and in low productivity or marginal lands makes it one of the most promising crops for ...
Anita Ierna +2 more
doaj +1 more source
Total areas of cervical marginal cement extrusion (mm2) evaluated by photography (Mean ± SD). [PDF]
, 2022 Total areas of cervical marginal cement extrusion (mm2) evaluated by photography (Mean ± SD).
Hao Feng (54208) +5 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Areaplanning in marginal areas [PDF]
, 2007 This project is also a comparative analysis between two cases: Lolland Kommune and Venise Verte, having both a marginal characteristic. The analyze of these two marginal areas makes us able to found out some dilemmas showing the crucial issues of ...
Sandberg, Rina +2 more
core
Piemonte. Tra stasi e sperimentazioni, un quadro chiaroscurale
ArchAlp, 2020 "The contemporary architectural production in the Alps of Piedmont has to be studied taking into consideration the contrasting phenomena of depopulation and tourism that have involved the mountain areas of the region during last century.
Roberto Dini, Antonio De Rossi
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Active ageing in marginal areas: a scoping review [PDF]
The purpose of this study is to give an overview of the extent, range, and nature of existing studies on active ageing in marginal areas. This overview will enable researchers, policymakers, and communities to understand the key challenges and ...
Paraciani, Rebecca, Garavaglia, Emma
core +1 more source