Results 61 to 70 of about 16,774,163 (333)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Dynamics of rural landscapes in marginal areas of northern Spain: Past, present, and future
Land Degradation and Development, 2018 European marginal areas hold multifunctional landscapes threatened by current changes in socio‐economy. Understanding both common and singular drivers behind the changes in the local socio‐economy and the landscapes is crucial to design sustainable ...
J. A. González Díaz +4 more
semanticscholar +1 more source
Policies for Sustainable Agriculture and Livelihood in Marginal Lands: A Review
Sustainability, 2021 Despite the substantial improvements in agricultural productivity owing to technological progress, the poor in agriculturally marginal areas are overlooked and left behind.
Hayatullah Ahmadzai +2 more
semanticscholar +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Animal Conservation, 2021 Misconceptions about species’ ecological preferences compromise conservation efforts. Whenever people and elephants share landscapes, human–elephant conflicts (HEC) occur in the form of crop raiding, elephant attacks on people and retaliatory actions ...
J. A. De la Torre +8 more
semanticscholar +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
, 2021 The Novel Corona Virus (COVID-19) has created tremendous negative impacts on the livelihood of the marginal population in Bangladesh. Many people working in the informal sector have lost their job and income due to the ongoing pandemic.
Mohammad Hossain
semanticscholar +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Biomass, Seed and Energy Yield of Cynara cardunculus L. as Affected by Environment and Season
Agronomy, 2020 Cynara cardunculus is a perennial plant that adapts well to Mediterranean climate conditions. The possibility of cultivating C. cardunculus with low or zero input and in low productivity or marginal lands makes it one of the most promising crops for ...
Anita Ierna +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source