Results 71 to 80 of about 46,996 (257)

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

Advanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi, Hanlou Yang, Junting Huang, Pengfei Wu, Shiying Zhou, Zunde Liao, Min Han, Zishan Chen, Xiaoyu Huang, Nan Ma, Jie Zhou, Mingqiang Li, Yiling Zhong   +12 more
wiley   +1 more source

Early marginal bone stability of dental implants placed in a transalveolarly augmented maxillary sinus: a controlled retrospective study of surface modification with calcium ions

International Journal of Implant Dentistry, 2017
Background Recently, components of the extracellular cellular matrix have been assessed to enhance the biological response to dental implants. This study aims to assess the effect of surface modification with calcium ions on the early marginal bone loss ...
Eduardo Anitua, Laura Piñas, Mohammad Hamdan Alkhraisat   +2 more
doaj   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

MECHANICAL EFFECT OF SIMULATED MARGINAL BONE RESORPTION ON NARROW DIAMETER IMPLANT IN MANDIBULAR RETAINED OVERDENTURE (IN-VITRO STUDY) [PDF]

Alexandria Dental Journal
Background: Marginal bone resorption affects implant stability and long-term success of mandibular overdentures. This study evaluates the biomechanical impact of bone resorption on narrow-diameter implants (NDIs) using Ball & Socket attachment ...
Mahmoud Abbas, Eman Alrafah, Sara Kamal
doaj   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Clinical and Radiographic Evaluation of Effect of Ellagic Acid on Osseointegration Around Dental Implants: An Original Research

Journal of Pharmacy and Bioallied Sciences
Objective: To evaluate the clinical and radiographic effects of ellagic acid on osseointegration around dental implants. Materials and Methods: A total of 60 patients, aged between 25 and 55 years, requiring dental implants, were designated for the study.
Mehjubah, Ghanta Chaitanya, Syeda Tawkhira Tabasum, Tupili Murali Krishna, Deepak Kolte, Ashvin Wagh, Rahul Tiwari   +6 more
doaj   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Survival and Marginal Bone Loss in Immediate Post-Extraction Implants versus Delayed Implants: A Systematic Review and Meta-Analysis

Oral
There are a series of protocols regarding the placement of dental implants after tooth extraction. The advantages and disadvantages that determine the procedure and timing of each dental implant placement process are key to achieving success.
Alba Portal-Solera, Beatriz Pardal-Peláez   +1 more
doaj   +1 more source

Marginal bone loss in the adult population in the county of Skåne, Sweden.

Swedish dental journal, 2013
The aim of this study was to investigate the prevalence and extent of periodontal disease registered as marginal bone loss and subject characteristics in the adult population in the county of Skåne in Sweden. One thousand individuals, 20-89 years old, were randomly selected and 451 subjects agreed to participate in the study.
Wahlin, Åsa, Jansson, Henrik, Klinge, Björn, Lundegren, Nina, Åkerman, Sigvard, Norderyd, Ola   +5 more
openaire   +2 more sources