Results 71 to 80 of about 2,594,639 (259)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Characterizing Convexity of Games using Marginal Vectors [PDF]

open access: yes
In this paper we study the relation between convexity of TU games and marginal vectors.We show that if specfic marginal vectors are core elements, then the game is convex.We characterize sets of marginal vectors satisfying this property, and we derive ...
Velzen, S. van   +2 more
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Drivers of Changing Interannual Variability in Autumn‐Early Winter Arctic Sea Ice (1950–2024)

open access: yesGeophysical Research Letters
Arctic sea ice has undergone a pronounced decline over recent decades, yet the drivers of its interannual variability remains unclear. Here we utilize standard deviation to assess long‐term changes in autumn‐early winter (October–December) Arctic sea ice
Lejiang Yu, Shiyuan Zhong, Timo Vihma
doaj   +1 more source

Dose reduction in digital radiography based on the significance of marginal contrast detectability. [PDF]

open access: yesJ Appl Clin Med Phys, 2021
Scott AW   +5 more
europepmc   +1 more source

A New Approach to Testing Marginal Productivity Theory [PDF]

open access: yes
We address the long standing question of whether production factors are paid their marginal products. We propose a new approach that circumvents the need to specify production functions and to compare marginal products to factor payments. Our approach is
Weiser, Constantin, Biewen, Martin
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Port Economics in Search of an Audience: The Public Life of Marginal Social Cost Pricing for Ports, 1970-2000

open access: yesŒconomia, 2019
Economics and its sub-disciplines often developed in close relationship with its audiences. This paper examines the public life of one particular case, the idea of marginal social cost pricing for ports, by highlighting two key episodes.
Thomas Vanoutrive, P.W. Zuidhof
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

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