Results 51 to 60 of about 281,643 (258)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Dental Research JournalBackground: The incorporation of digital techniques has gained popularity in the fabrication of fixed dental prostheses (FDPs) over the last decade; however, limited evidence exists regarding the marginal and internal fit when using conventional versus ...
Anamika Sinha +5 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
On the marginal likelihood and crossvalidation
, 2020 In Bayesian statistics, the marginal likelihood, also known as the evidence, is used to evaluate model fit as it quantifies the joint probability of the data under the prior.
Fong, E. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Human consumption of seaweed and freshwater aquatic plants in ancient Europe
Nature Communications, 2023 During the Mesolithic in Europe, there is widespread evidence for an increase in exploitation of aquatic resources. In contrast, the subsequent Neolithic is characterised by the spread of farming, land ownership, and full sedentism, which lead to the ...
Stephen Buckley +7 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsTraditional prices at the distribution level cannot efficiently guide the comprehensive cost recovery. To this end, this paper proposes a novel integrated nodal price by solving a comprehensive investment problem.
Zhaobin Wei +7 more
doaj +1 more source
Gradient phonological relationships: Evidence from vowels in French
Glossa, 2017 The dichotomy of contrastive and allophonic phonological relationships has a long-standing tradition in phonology, but there is growing research that points to phonological relationships that fall between contrastive and allophonic.
Sophia Stevenson, Tania Zamuner
doaj +2 more sources
Pseudo-marginal algorithms with multiple CPUs
, 2014 The emergence of pseudo-marginal algorithms has led to improved computational efficiency for dealing with complex Bayesian models with latent variables.
Drovandi, Christopher C.
core