Results 41 to 50 of about 281,643 (258)

Estimating marginal returns to education [PDF]

This paper estimates the marginal returns to college for individuals induced to enroll in college by different marginal policy changes. The recent instrumental variables literature seeks to estimate this parameter, but in general it does so only under ...
James Heckman, Edward Vytlacil, Pedro Carneiro   +2 more
core   +4 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Factors associated with implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis [PDF]

Xin yixue
Objective To analyze the factors related to implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis. Methods One hundred and ninety-five elderly patients with severe periodontitis who underwent implant ...
LI Yue, MA Yanru
doaj   +1 more source

Image Enhancement via Special Functions and Its Application for Near Infrared Imaging

Global Challenges, 2023
Image enhancement is important given that it can be used to highlight the area of interest in the images. This article designs four filters via special function for realizing image enhancement.
Ruoxi Yang, Long Chen, Ling Zhang, Zongan Li, Yingcheng Lin, Ye Wu   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Marginal Benefit of Industrial Water Use in Northern China and Its Influencing Factors

Renmin Zhujiang, 2022
With the data on the economic indicators,such as industrial water use,industrial added value,fixed-asset investment,and the number of employees,of the northern region for 2011—2020,this study employed an improved Cobb-Douglas production function to ...
DIAO Zicheng, ZHAO Jing, HAN Yuping
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Marginal deformations of SU(2) k WZW model boundary states in open string field theory

Journal of High Energy Physics
We attempt to describe the moduli space of boundary states in the SU(2) k WZW model by constructing marginally deformed solutions in open string field theory in the level truncation approximation.
Matěj Kudrna
doaj   +1 more source

Marginal eyespots on butterfly wings deflect bird attacks under low light intensities with UV wavelengths. [PDF]

PLoS ONE, 2010
Predators preferentially attack vital body parts to avoid prey escape. Consequently, prey adaptations that make predators attack less crucial body parts are expected to evolve.
Martin Olofsson, Adrian Vallin, Sven Jakobsson, Christer Wiklund   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source