Results 51 to 60 of about 5,052,793 (311)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Analysis of Ferquency Maximum Flood in Mountain basin (Case study : Armand station) [PDF]
علوم و مهندسی آبیاری, 2012 A bivariate extreme value distribution, namely the Gumbel mixed model constructed from Gumbel marginal distributions is employed to analyze the joint distribution of correlated flood peak (probable maximum flood) and amount.
D. Rahimi, A. Baratian
doaj
A product autoregressive model with log-Laplace marginal distribution
Statistica, 2013 The log-Laplace distribution and its properties are considered. Some important properties like multiplicative infinite divisibility, geometric multiplicative infinite divisibility and self-decomposability are discussed.
Kanichukattu K. Jose, Manu Mariam Thomas
doaj +1 more source
Marginal Distribution Multi-Target Bayes Filter With Assignment of Measurements
IEEE Access, 2020 This work proposes a marginal distribution multi-target Bayes filter with assignment of measurements to track multiple targets in the presence of an unknown and variable number of targets, clutter, and missed detections.
Zong-Xiang Liu, Mian Wu, Jie Gan
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Very simple marginal effects in some discrete choice models [PDF]
I show a simple back-of-the-envelope method for calculating marginal effects in binary choice and count data models. The approach suggested here focuses attention on marginal effects at different points in the distribution of the dependent variable ...
Kevin J. Denny
core +2 more sources
Inference with the Median of a Prior
Entropy, 2006 We consider the problem of inference on one of the two parameters of a probability distribution when we have some prior information on a nuisance parameter.
Ali Mohammad-Djafari, Adel Mohammadpour
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source