Results 81 to 90 of about 5,269,728 (309)
Marginal parameter distribution with correlation matrix estimated through Bayesian approach.
, 2015 The diagonal cells show the marginal distribution for individual parameters. The off-diagonal cells show the pairwise joint distribution of parameters and their corresponding correlation coefficient.
Ann Rundell (777603) +6 more
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Autoregressive Models Estimation Selection with Known Marginal Distribution
Ibn Al-Haitham Journal for Pure and Applied SciencesA time series is a sequence of observations recorded at regular intervals. Time series analysis has applications in diverse fields such as finance, stock prices, economics, environmental science, and social network data analysis.
Israa Amer Flayyih, Basad Al-sarray
doaj +1 more source
Efficient Robbins–Monro procedure for multivariate binary data
Statistical Theory and Related Fields, 2018 This paper considers the problem of jointly estimating marginal quantiles of a multivariate distribution. A sufficient condition for an estimator that converges in probability under a multivariate version of Robbins–Monro procedure is provided.
Cui Xiong, Jin Xu
doaj +1 more source
A seasonal Integer-Valued AR(1) model with delaporte marginal distribution [PDF]
مدلسازی پیشرفته ریاضیReal-count data time series often show the phenomenon of over-dispersion. In this paper, we introduce the first-order integer-valued autoregressive process with seasonal structure.
Maryam Shalbaf +2 more
doaj +1 more source
Different Ecological Niches of Poisonous Aristolochia clematitis in Central and Marginal Distribution Ranges-Another Contribution to a Better Understanding of Balkan Endemic Nephropathy. [PDF]
Plants (Basel), 2023 Brzić I +14 more
europepmc +1 more source