Results 61 to 70 of about 1,321,254 (310)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

INTEGRATING AGRO-ECOSYSTEM ANALYSIS INTO AGRICULTURAL EXTENSION AND ADVISORY SERVICES IN MARGINAL ENVIRONMENTS OF EGYPT: THE CASE OF SAHL EL-TINA, SINAI PENINSULA [PDF]

Egyptian Journal of Desert Research, 2017
The agro-ecosystem includes not only the environmental setting, but also, the agricultural technology system, as well as, the social setting, which draw people's behavior towards natural resources.
Mostafa Badr
doaj   +1 more source

Euro Effects on the Intensive and Extensive Margins of Trade [PDF]

SSRN Electronic Journal, 2006
We estimate that the euro has increased trade within the eurozone by about 26 per cent and trade between the eurozone and outsiders by about 12 per cent on average for the years 2002- 2005 compared to 1995-1998. The percentage increases were smaller for products that were exported every year during the sample period than for products that were not ...
Flam, Harry, Nordström, Håkan
openaire   +6 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

THE CENOZOIC GRABEN IN THE MARGINAL SUTURE ZONE OF THE SIBERIAN CRATON: INTERIOR STRUCTURAL FEATURES AND TECTONIC STRESS RECONSTRUCTIONS

Геодинамика и тектонофизика
Marginal suture zones of ancient platforms are deep-seated fault zones separating the craton from the mobile belt. Of particular interest is the Pribaikalian marginal suture of the Siberian craton, activated during the Cenozoic rifting.
A. V. Cheremnykh, A. A. Bobrov, I. K. Dekabryov, A. S. Cheremnykh, G. A. Gridin, D. V. Pavlov, A. A. Yuriev   +6 more
doaj   +1 more source

Virginia Cooperative Extension Volunteer Screening Guidelines

, 2020
Frequently asked questions for Virginia Cooperative Extension volunteers.

core  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Scattering Polarimetry in the Hard X-ray Range

Instruments
In one and a half years, the Imaging X-ray Polarimetry Explorer has demonstrated the role and the potentiality of Polarimetry in X-ray Astronomy. The next steps include extension to higher energies.
Enrico Costa
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Firm size and the extensive margin

Economic and Business Review, 2011
In this paper we rely on firm-product-destination level data to analyze Hungarian trade expansion between 1992 and 2003. We decompose trade growth to the number of firms, the number of markets and products per firm, and analyze these dimensions by firm size. We also distinguish between new firms and continuing exporters.
László Halpern, Balázs Muraközy
openaire   +3 more sources