Results 51 to 60 of about 87,704 (248)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

الاتجاهات الحديثة والمعاصرة في الجغرافيا الاجتماعية وعلاقتها بجغرافية السكان في الفترة من 1995-2017م بحث مرجعي [PDF]

open access: yesMaǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīd
يتناول البحث الاتجاهات الحديثة والمعاصرة في الجغرافيا الاجتماعية وجغرافية السكان في الفترة من 1995 إلى 2017، ويستعرض العلاقة الوثيقة بين هذين الفرعين من الجغرافيا.
ياسر عبد العظيم عبد الموجود سمك   +1 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Socio-Economic Marginalization and Compliance Motivation Among Students and Freeters in Japan

open access: yesFrontiers in Psychology, 2019
This study examines the compliance motivation of students and Freeters when facing a marginalization risk situation evoked by priming. Freeter (part-time employers), NEET (not in education, employment, or training), and Hikikomori (social withdrawal ...
I-Ting Huai-Ching Liu   +2 more
doaj   +1 more source

Faces and causes of Roma marginalization: Experiences from Hungary

open access: yes, 2014
The "Faces and Causes of Roma Marginalization in Local Communities" inquiry explored the economic, political, demographic, and social forces at municipal and community level which shape practices and consequences of social exclusion and potential ...
Virág, Tünde, Váradi, Monika
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Youth Are Not All the Same: On the Appropriateness and Limits of Participatory Methods in Youth Research

open access: yesSocial Sciences
The field of youth studies has traditionally promoted participatory methods, assuming that young people prefer creativity over standard methods like traditional ethnography or one-to-one interviews.
Elena Butti
doaj   +1 more source

Faces and causes of Roma marginalization: Experiences from Romania

open access: yes, 2014
The "Faces and Causes of Roma Marginalization in Local Communities" inquiry explored the economic, political, demographic, and social forces at municipal and community level which shape practices and consequences of social exclusion and potential ...
Vincze, Enikő
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Marginality Marginalization Imprisonment

open access: yesCritical Hermeneutics, 2022
Emilio Baccarini
doaj   +1 more source

Home - About - Disclaimer - Privacy