Results 11 to 20 of about 4,000,394 (237)

Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations [PDF]

open access: yes, 2006
Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia).
Müller, Stefan, Volleth, M.
core   +1 more source

Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype

open access: yesEMBO Molecular Medicine, 2021
Batten diseases (BDs) are a group of lysosomal storage disorders characterized by seizure, visual loss, and cognitive and motor deterioration. We discovered increased levels of globotriaosylceramide (Gb3) in cellular and murine models of CLN3 and CLN7 ...
Chiara Soldati   +22 more
doaj   +1 more source

Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma

open access: yesFrontiers in Oncology, 2020
Dysregulation of the kynurenine pathway has been regarded as a mechanism of tumor immune escape by the enzymatic activity of indoleamine 2, 3 dioxygenase and kynurenine production. However, the immune-modulatory properties of other kynurenine metabolites
Soudabeh Rad Pour   +17 more
doaj   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

The Use of Problem-Based Learning Physics E-Module on Global Warming Material: High School Students Perception

open access: yesJournal of Innovative Science Education, 2023
Global warming as one of the physics materials, is a topic that tends to be abstract so it causes difficulties for students. In addition, limited time for learning activities in class is an obstacle to achieving optimal understanding.
Julius Wilson   +2 more
doaj  

Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma

open access: yesBMC Cancer, 2019
Background Patients with metastatic renal carcinoma frequently have pre-existing renal impairment and not infrequently develop worsening renal function as a complication of their treatment.
Karin Purshouse   +5 more
doaj   +1 more source

Correction: Magmas Overexpression Inhibits Staurosporine Induced Apoptosis in Rat Pituitary Adenoma Cell Lines.

open access: yesPLoS ONE, 2013
[This corrects the article on p. e75194 in vol. 8.].
Federico Tagliati   +6 more
doaj   +1 more source

CONTROLE de plantas indesejadas, como a maria mole e o caruru: primeira semana.

open access: yes, 2023
Esta semana, você fica ligado no Prosa Rural para obter informações importantes sobre o controle de plantas indesejadas como a maria mole e o caruru.

core   +1 more source

Cyclo-Oxygenase 2 Modulates Chemoresistance in Breast Cancer Cells Involving NF-κB

open access: yesCellular Oncology, 2009
Background: Breast cancer cells can develop chemoresistance after prolonged exposure to cytotoxic drugs due to expression of the multi drug resistance (MDR) 1 gene.
Maria Chiara Zatelli   +5 more
doaj   +1 more source

Spatial and temporal distribution of weeds in no-tillage system

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
Brazil is one of the largest grain producers in the world, due to its extensive arable land and favorable climate for the cultivation of any species. The production could be higher, but problems such as competition between crops and weeds reduces crop ...
Eduardo L. Bottega   +4 more
doaj   +1 more source

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