Results 51 to 60 of about 126,022 (347)

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

British Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung, Louisa Picco, Aili V. Langford, Rose Laing, Jana Dostal, Suzanne Nielsen   +5 more
wiley   +1 more source

The grass is not always greener: a multi-institutional pilot study of marijuana use and acute pain management following traumatic injury

Patient Safety in Surgery, 2018
Background Widespread legislative efforts to legalize marijuana have increased the prevalence of marijuana use and abuse. The effects of marijuana on pain tolerance and analgesic pain management in the acute pain setting have not been reported.
Kristin Salottolo, Laura Peck, Allen Tanner II, Matthew M. Carrick, Robert Madayag, Emmett McGuire, David Bar-Or   +6 more
doaj   +1 more source

Addressing Youth Perceptions of Harm in Marijuana Prevention Programming [PDF]

, 2018
The inverse relationship between perception of harm and substance use is clearly supported by decades of research – youth are less likely to engage in substance use when it is seen as harmful.
,, Dash, Kimberly, Esrick, Joshua, Quinlan, Kristen J, Rots, Gisela, Valenti, Maria   +5 more
core   +1 more source

Cannabis; epidemiological, neurobiological and psychopathological issues: an update [PDF]

, 2017
This document is the Accepted Manuscript version of the following article: Maria Antonietta De Luca, Gaetano Di Chiara, Cristina Cadoni, Daniele Lecca, Laura Orsolini, Duccio Papanti, John Corkery, Fabrizio Schifano, 'Cannabis; Epidemiological ...
Cadoni, Cristina, Corkery, John, De Luca, Maria Antonietta, Di Chiara, Gaetano, Lecca, Daniele, Orsolini, Laura, Papanti, Duccio, Schifano, Fabrizio   +7 more
core   +3 more sources

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

Comparing teen substance use in northern New Hampshire to rural use nationwide [PDF]

, 2013
Using data administered in 2011 from the Carsey Institute’s Coös Youth Study and the National Survey on Drug Use and Health, this brief compares teen substance use patterns in New Hampshire’s most rural county to patterns among rural youth nationwide ...
Van Gundy, Karen T.
core   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

Drug Testing and Analysis, EarlyView.
ABSTRACT Hair analysis is increasingly used in forensic toxicology; however, result interpretation may be influenced by cosmetic hair treatments. Although the effects of bleaching, dyeing, and thermal straightening have already been evaluated, data on permanent chemical hair straightening are scarce, particularly under in vivo conditions.
Miriam Blanco‐Ces, Ana de‐Castro‐Ríos, María Cobo‐Golpe, Ángela López‐Rabuñal, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of cross-addictive behaviour among Greenland Inuit: evidence from the cross-sectional Inuit health in transition Greenland survey 2006–2010 [PDF]

International Journal of Circumpolar Health, 2013
Background and objectives. Public health research has pointed to alcohol and substance abuse as the most significant public health challenges in Greenland with the negative impact on families and communities that entail, but few studies have investigated
Christina Viskum Lytken Larsen, Tine Curtis, Peter Bjerregaard   +2 more
doaj   +1 more source

Do Black and White Americans Hold Different Views on Marijuana Legalization? Analyzing the Impact of “The War on Drugs” on Racialized Perceptions of Legalizing Marijuana [PDF]

, 2018
This study examines whether Black and White Americans develop their views regarding the legalization of marijuana based on different life experiences and, specifically, their involvement with the criminal justice system and drug laws.
Kaminoff, Benjamin S
core   +1 more source