Results 61 to 70 of about 9,018,466 (292)

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Proceedings of the 7th Irish Shellfish Safety Workshop [PDF]

open access: yes, 2007
This document outlines the proceedings of the 7th Irish Shellfish Safety Scientific Workshop. This event was organised by the Marine Institute, the Food Safety Authority of Ireland and Bord Iascaigh Mhara to discuss the methods and advances of food ...
Marine Institute
core   +2 more sources

Oceans of Opportunity - Exploring Ireland’s Marine Resources: Review of Projects 2000–2005

open access: yes, 2006
This publication gives an overview of projects and some of the achievements of the research and development activity funded under the Marine RTDI in the current National Development Plan (2000–2006).
Marine Institute
core   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Proceedings of the 5th Irish Shellfish Safety Workshop, Rosscarbery, October 28th 2004 [PDF]

open access: yes, 2005
This document outlines the proceedings of the 5th Irish Shellfish Safety Scientific Workshop. This event was organised by the Marine Institute, the Food Safety Authority of Ireland and Bord Iascaigh Mhara to discuss the methods and advances of food ...
Marine Institute
core   +2 more sources

What do people make of “Ecosystem Based Fisheries Management”?

open access: yesFrontiers in Marine Science
The topic of Ecosystem Based Fisheries Management (EBFM) and related terminology has attracted considerable scholarly debate and inspired regulatory interventions across Europe.
Marie Briguglio   +3 more
doaj   +1 more source

Marine-based ecological education: marine discovery centres, millennium kids, environmental citizenship, and a vision for an eco-camp [PDF]

open access: yes, 2006
The aim of this thesis is to gain knowledge and understanding about Marine-Based Ecological Education and then apply this knowledge and understanding to form the vision of an Eco-Camp in Western Australia. This has been done in three stages.
La Mar, Brendan Paul
core  

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

open access: yesAdvanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal   +25 more
wiley   +1 more source

Marine Biotechnology Task Force Report [PDF]

open access: yes, 2017
Marine biotechnology is a rapidly growing area that is recognised, by policy makers and the enterprise sector, as offering significant potential to develop market opportunities for new products and processes by enabling greater utilisation of marine ...
Marine Biotechnology Task
core   +2 more sources

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

open access: yesAdvanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li   +11 more
wiley   +1 more source

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