Results 31 to 40 of about 1,006,359 (227)

Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

open access: yesMarine Drugs, 2020
The current emergency due to the worldwide spread of the COVID-19 caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a great concern for global public health.
Davide Gentile   +5 more
semanticscholar   +1 more source

A Review Study on Macrolides Isolated from Cyanobacteria

open access: yesMarine Drugs, 2017
Cyanobacteria are rich sources of structurally-diverse molecules with promising pharmacological activities. Marine cyanobacteria have been proven to be true producers of some significant bioactive metabolites from marine invertebrates.
Mengchuan Wang   +3 more
doaj   +1 more source

Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. [PDF]

open access: yes, 2017
Natural product screening programs have uncovered molecules from diverse natural sources with various biological activities and unique structures. However, much is yet underexplored and additional information is hidden in these exceptional collections ...
Ackermann, Gail   +14 more
core   +3 more sources

CMNPD: a comprehensive marine natural products database towards facilitating drug discovery from the ocean

open access: yesNucleic Acids Res., 2020
Marine organisms are expected to be an important source of inspiration for drug discovery after terrestrial plants and microorganisms. Despite the remarkable progress in the field of marine natural products (MNPs) chemistry, there are only a few open ...
Chuanyu Lyu   +6 more
semanticscholar   +1 more source

AlgM4: A New Salt-Activated Alginate Lyase of the PL7 Family with Endolytic Activity

open access: yesMarine Drugs, 2018
Alginate lyases are a group of enzymes that catalyze the depolymerization of alginates into oligosaccharides or monosaccharides. These enzymes have been widely used for a variety of purposes, such as producing bioactive oligosaccharides, controlling the ...
Guiyuan Huang   +7 more
doaj   +1 more source

Marine Microbial Natural Products [PDF]

open access: yesJundishapur Journal of Natural Pharmaceutical Products, 2014
Isolation of diverse chemical compounds from marine organisms implies a promising source of natural products. Oceans cover nearly 70% of the earth’s surface and over 90% of the volume of its crust (1). Marine environment contains a variety of species, many of which have no terrestrial counterparts. Recently, trends in search of new drugs emphasize that
openaire   +2 more sources

Isolation and characterization of marine-derived actinomycetes with cytotoxic activity from the Red Sea coast

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2016
Objective: To isolate and evaluate the cytotoxic activity of different actinomycetes species isolated from the Red Sea coast in Sharm el-Sheikh, Egypt.
Mohamed Saleh Abdelfattah   +4 more
doaj   +1 more source

Natural Products from Marine Fungi

open access: yesMarine Drugs, 2020
Marine fungi have been studied since the first record of the species Sphaeria posidoniae (Halotthia posidoniae) on the rhizome of the sea grass Posidonia oceanica by Durieu and Montagne in 1846 [...]
Hee Jae Shin
doaj   +1 more source

Marine Cytotoxic Macrolides Haterumalides and Biselides, and Related Natural Products [PDF]

open access: yes, 2007
Marine animals and plants are rich sources of bioactive natural products. Haterumalides and biselides, isolated from Okinawan marine animals, are 14-membered macrolides with strong cytotoxicity against human cancer cell lines.
Hayakawa Ichiro   +3 more
core   +1 more source

Preparative Isolation and Purification of Lignans from Justicia procumbens Using High-Speed Counter-Current Chromatography in Stepwise Elution Mode

open access: yesMolecules, 2015
Lignans, which are recognized as main constituents in Justicia procumbens, have attracted considerable attention due to their pharmacological activities, including antitumor, anti-hepatitic, cytotoxic, anti-microbial, and anti-virus properties ...
Peijuan Zhou   +8 more
doaj   +1 more source

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