Results 31 to 40 of about 110,609 (253)

Preparative Isolation and Purification of Lignans from Justicia procumbens Using High-Speed Counter-Current Chromatography in Stepwise Elution Mode

Molecules, 2015
Lignans, which are recognized as main constituents in Justicia procumbens, have attracted considerable attention due to their pharmacological activities, including antitumor, anti-hepatitic, cytotoxic, anti-microbial, and anti-virus properties ...
Peijuan Zhou, Qijun Luo, Lijian Ding, Fang Fang, Ye Yuan, Juanjuan Chen, Jinrong Zhang, Haixiao Jin, Shan He   +8 more
doaj   +1 more source

Optimization of Fermentation Process for New Anti-Inflammatory Glycosylceramide Metabolite from Aspergillus sp.

Metabolites
A novel ceramide compound, named Aspercerebroside A (AcA), was successfully isolated from the ethyl acetate layer of the marine symbiotic fungus Aspergillus sp.
Yung-Husan Chen, Qiaoqiao Zhu, Jingyi Li, Rong Yang, Jingwen Zhang, Minxin You, Lianzhong Luo, Bingye Yang   +7 more
doaj   +1 more source

Effects of different combined regimens of cisplatin, metformin, and quercetin on nasopharyngeal carcinoma cells and subcutaneous xenografts

Scientific Reports, 2021
Cisplatin, metformin, and quercetin are all reliable anticancer drugs. However, it is unclear how effective their different combination regimens are on the growth of nasopharyngeal carcinoma cell line Sune-1 and subcutaneous xenograft in nude mice.
Zhongwei Chen, Zhen Zeng, Shanshan Zhu, Ying Zeng, Qihuang Lin, Lianzhong Luo, Xuan Hong   +6 more
doaj   +1 more source

Molecular Networking-Based Metabolome and Bioactivity Analyses of Marine-Adapted Fungi Co-cultivated With Phytopathogens

Frontiers in Microbiology, 2018
Fungi represent a rich source of bioactive metabolites and some are marketed as alternatives to synthetic agrochemicals against plant pathogens. However, the culturability of fungal strains in artificial laboratory conditions is still limited and the ...
Ernest Oppong-Danquah, Delphine Parrot, Martina Blümel, Antje Labes, Antje Labes, Deniz Tasdemir, Deniz Tasdemir   +6 more
doaj   +1 more source

Indole acetic acid and ACC deaminase from endophytic bacteria improves the growth of Solanum lycopersicum

Electronic Journal of Biotechnology, 2016
Background: Endophytic bacteria are ubiquitous in all plant species contributing in host plant's nutrient uptake and helping the host to improve its growth.
Abdul Latif Khan, Boshra Ahmed Halo, Ali Elyassi, Sajid Ali, Khadija Al-Hosni, Javid Hussain, Ahmed Al-Harrasi, In-Jung Lee   +7 more
doaj   +1 more source

Diversity, Bioactivity Profiling and Untargeted Metabolomics of the Cultivable Gut Microbiota of Ciona intestinalis

Marine Drugs, 2020
It is widely accepted that the commensal gut microbiota contributes to the health and well-being of its host. The solitary tunicate Ciona intestinalis emerges as a model organism for studying host–microbe interactions taking place in the gut, however ...
Caroline Utermann, Vivien A. Echelmeyer, Ernest Oppong-Danquah, Martina Blümel, Deniz Tasdemir   +4 more
doaj   +1 more source

Pyrenosetins A–C, New Decalinoylspirotetramic Acid Derivatives Isolated by Bioactivity-Based Molecular Networking from the Seaweed-Derived Fungus Pyrenochaetopsis sp. FVE-001

Marine Drugs, 2020
Marine algae represent a prolific source of filamentous fungi for bioprospecting. In continuation of our search for new anticancer leads from fungi derived from the brown alga Fucus vesiculosus, an endophytic Pyrenochaetopsis sp. FVE-001 was selected for
Bicheng Fan, Pradeep Dewapriya, Fengjie Li, Martina Blümel, Deniz Tasdemir   +4 more
doaj   +1 more source

Mining the Metabolome and the Agricultural and Pharmaceutical Potential of Sea Foam-Derived Fungi

Marine Drugs, 2020
Sea foam harbors a diverse range of fungal spores with biological and ecological relevance in marine environments. Fungi are known as the producers of secondary metabolites that are used in health and agricultural sectors, however the potentials of sea ...
Ernest Oppong-Danquah, Cristina Passaretti, Orazio Chianese, Martina Blümel, Deniz Tasdemir   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source