Results 61 to 70 of about 1,006,359 (227)

Bioactivity Profiling and Untargeted Metabolomics of Microbiota Associated with Mesopelagic Jellyfish Periphylla periphylla

Marine Drugs, 2023
The marine mesopelagic zone extends from water depths of 200 m to 1000 m and is home to a vast number and diversity of species. It is one of the least understood regions of the marine environment with untapped resources of pharmaceutical relevance.
Ernest Oppong-Danquah, Martina Miranda, Martina Blümel, Deniz Tasdemir   +3 more
doaj   +1 more source

Nontargeted biomonitoring of halogenated organic compounds in two ecotypes of bottlenose dolphins (Tursiops truncatus) from the Southern California Bight. [PDF]

, 2015
Targeted environmental monitoring reveals contamination by known chemicals, but may exclude potentially pervasive but unknown compounds. Marine mammals are sentinels of persistent and bioaccumulative contaminants due to their longevity and high trophic ...
Aluwihare, Lihini I, Chivers, Susan J, Danil, Kerri, Dodder, Nathan G, Hoh, Eunha, Mackintosh, Susan A, Maruya, Keith A, Shaul, Nellie J, Weller, David W   +8 more
core   +3 more sources

Insights about clinically approved and Preclinically investigated marine natural products

, 2020
Since the early research efforts focusing on bioactive marine substances such as spongouridine, from the marine sponge Cryptotethya crypta, marine natural products (MNPs) have arisen as a robust and sustainable supplier for bioactive drug leads.
M. Ghareeb, M. Tammam, A. El‐Demerdash, A. Atanasov   +3 more
semanticscholar   +1 more source

Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018)

Marine Life Science & Technology, 2022
Marine sponges are productive sources of bioactive secondary metabolites with over 200 new compounds isolated each year, contributing 23% of approved marine drugs so far.
Li-Li Hong, Yaoguang Ding, Wei Zhang, Hou‐Wen Lin   +3 more
semanticscholar   +1 more source

Heterologous Expression and Functional Verification of Extracellular Carbonic Anhydrases in Bacillus safensis yw6 from Mariana Trench

Molecules
The exploration and exploitation of deep-sea microbial resources is of great scientific value for understanding biological evolution under extreme conditions.
Xinyu Wang, Pengna Wang, Hancheng Zhao, Yingying He, Changfeng Qu, Jinlai Miao   +5 more
doaj   +1 more source

Bioprospecting cultivable bacteria associated with deep sea (mesopelagic) fish of the North Atlantic Ocean

Natural Products and Bioprospecting
The microbiota associated with fish is increasingly recognized as a valuable source of bioactive metabolites for pharmaceutical application. The mesopelagic zone, a deep and unique ecosystem with a diverse biological community, is among the least studied
Ernest Oppong-Danquah, Jana Heumann, Hannah Moosbauer, Martina Blümel, Arlette Wenzel-Storjohann, Deniz Tasdemir   +5 more
doaj   +1 more source

Influence of polyherbal formulation (AquaImmu) as a potential growth promotor and immunomodulator in shrimp Penaeus monodon

Aquaculture Reports, 2016
Growth enhancing and immunostimulating potential of a polyherbal formulation AquaImmu was assessed in Penaeus monodon outdoor culture system which was tested for 90 days.
M. Navin Chandran, S. Moovendhan, A.M. Suganya, A. Tamilselvi, Bebin, G. Immanuel, A. Palavesam   +6 more
doaj   +1 more source

Metabolomics and Microbiomics Insights into Differential Surface Fouling of Three Macroalgal Species of Fucus (Fucales, Phaeophyceae) That Co-Exist in the German Baltic Sea

Marine Drugs, 2023
The brown algal genus Fucus provides essential ecosystem services crucial for marine environments. Macroalgae (seaweeds) release dissolved organic matter, hence, are under strong settlement pressure from micro- and macrofoulers.
Ernest Oppong-Danquah, Martina Blümel, Deniz Tasdemir   +2 more
doaj   +1 more source

Influence of OSMAC-Based Cultivation in Metabolome and Anticancer Activity of Fungi Associated with the Brown Alga Fucus vesiculosus

Marine Drugs, 2019
The fungi associated with marine algae are prolific sources of metabolites with high chemical diversity and bioactivity. In this study, we investigated culture-dependent fungal communities associated with the Baltic seaweed Fucus vesiculosus. Altogether,
Bicheng Fan, Delphine Parrot, Martina Blümel, Antje Labes, Deniz Tasdemir   +4 more
doaj   +1 more source

Polyketides and Meroterpenes from the Marine-Derived Fungi Aspergillus unguis 158SC-067 and A. flocculosus 01NT-1.1.5 and Their Cytotoxic and Antioxidant Activities

Marine Drugs, 2021
Ten secondary metabolites, including a new grifolin analog, grifolin B (1); a new homovalencic acid derivative, 12-hydroxyhomovalencic acid (7); and a compound isolated from a natural source for the first time (9), along with seven known compounds ...
Cao Van Anh, Jong Soon Kang, Byeoung-Kyu Choi, Hwa-Sun Lee, Chang-Su Heo, Hee Jae Shin   +5 more
doaj   +1 more source