Results 1 to 10 of about 74,091 (305)

First continuous marine sponge cell line established [PDF]

Scientific Reports, 2023
The potential of sponge-derived chemicals for pharmaceutical applications remains largely unexploited due to limited available biomass. Although many have attempted to culture marine sponge cells in vitro to create a scalable production platform for such
Kylie Hesp, Jans M. E. van der Heijden, Stephanie Munroe, Detmer Sipkema, Dirk E. Martens, Rene H. Wijffels, Shirley A. Pomponi   +6 more
doaj   +5 more sources

Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors [PDF]

Marine Drugs, 2020
Marine sponge holobionts, defined as filter-feeding sponge hosts together with their associated microbiomes, are prolific sources of natural products. The inventory of natural products that have been isolated from marine sponges is extensive. Here, using
Ipsita Mohanty, Sheila Podell, Jason S. Biggs, Neha Garg, Eric E. Allen, Vinayak Agarwal   +5 more
doaj   +4 more sources

Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures

mSystems, 2021
Marine sponge holobionts are prolific sources of natural products. One of the most geographically widespread classes of sponge-derived natural products is the bromotyrosine alkaloids.
Ipsita Mohanty, Subhasish Tapadar, Samuel G. Moore, Jason S. Biggs, Christopher J. Freeman, David A. Gaul, Neha Garg, Vinayak Agarwal   +7 more
doaj   +3 more sources

Cell interactions and osteogenic differentiation on marine sponge-derived scaffolds: a systematic review [PDF]

Biofunctional Materials, 2023
Marine sponges, with their unique blend of organic and inorganic components, hold promise as biomaterials for bone tissue engineering. In this study, we systematically reviewed and comprehensively analysed in vitro assays evaluating osteogenic cell ...
Jonas de Araújo Silva, Adriel Filipe Santos Braga da Silva, Amanda Sardeli Alqualo, Beatriz Viegas, Ana Cláudia Muniz Rennó, Renata Neves Granito   +5 more
doaj   +1 more source

Microbiome species diversity and seasonal stability of two temperate marine sponges Hymeniacidon perlevis and Suberites massa

Environmental Microbiome, 2023
Background Marine sponges are diverse and functionally important members of marine benthic systems, well known to harbour complex and abundant symbiotic microorganisms as part of their species-specific microbiome.
Claire E. Lamb, Joy E. M. Watts
doaj   +1 more source

Sponges and Their Symbionts as a Source of Valuable Compounds in Cosmeceutical Field

Marine Drugs, 2021
In the last decades, the marine environment was discovered as a huge reservoir of novel bioactive compounds, useful for medicinal treatments improving human health and well-being.
Roberta Esposito, Nadia Ruocco, Thomas Viel, Serena Federico, Valerio Zupo, Maria Costantini   +5 more
doaj   +1 more source

Marine Sponge is a Promising Natural Source of Anti-SARS-CoV-2 Scaffold

Frontiers in Pharmacology, 2021
The current pandemic caused by SARS-CoV2 and named COVID-19 urgent the need for novel lead antiviral drugs. Recently, United States Food and Drug Administration (FDA) approved the use of remdesivir as anti-SARS-CoV-2.
Alshaimaa M. Hamoda, Alshaimaa M. Hamoda, Alshaimaa M. Hamoda, Bahgat Fayed, Bahgat Fayed, Naglaa S. Ashmawy, Naglaa S. Ashmawy, Abdel-Nasser A. El-Shorbagi, Abdel-Nasser A. El-Shorbagi, Rania Hamdy, Rania Hamdy, Sameh S. M. Soliman, Sameh S. M. Soliman   +12 more
doaj   +1 more source

Marine Sponges in a Snowstorm – Extreme Sensitivity of a Sponge Holobiont to Marine Oil Snow and Chemically Dispersed Oil Pollution

Frontiers in Microbiology, 2022
Holobionts formed by a host organism and associated symbionts are key biological units in marine ecosystems where they are responsible for fundamental ecosystem services. Therefore, understanding anthropogenic impacts on holobionts is essential. Sponges (
Johanne Vad, Laura Duran Suja, Stephen Summers, Theodore B. Henry, J. Murray Roberts   +4 more
doaj   +1 more source

Comparative Metagenomic Analysis of Biosynthetic Diversity across Sponge Microbiomes Highlights Metabolic Novelty, Conservation, and Diversification

mSystems, 2022
Marine sponges and their microbial symbiotic communities are rich sources of diverse natural products (NPs) that often display biological activity, yet little is known about the global distribution of NPs and the symbionts that produce them.
Catarina Loureiro, Anastasia Galani, Asimenia Gavriilidou, Maryam Chaib de Mares, John van der Oost, Marnix H. Medema, Detmer Sipkema   +6 more
doaj   +1 more source

From friends to foes: fungi could be emerging marine sponge pathogens under global change scenarios

Frontiers in Microbiology, 2023
Global change, experienced in the form of ocean warming and pollution by man-made goods and xenobiotics, is rapidly affecting reef ecosystems and could have devastating consequences for marine ecology. Due to their critical role in regulating marine food
Yordanis Pérez-Llano, Yordanis Pérez-Llano, Luis Andrés Yarzábal Rodríguez, Esperanza Martínez-Romero, Alan D. W. Dobson, Nina Gunde-Cimerman, Vitor Vasconcelos, Vitor Vasconcelos, Ramón Alberto Batista-García, Ramón Alberto Batista-García   +9 more
doaj   +1 more source