Results 1 to 10 of about 1,690 (206)
Terpene biosynthesis in marine sponge animals [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2023 Sea sponges are the largest marine source of small-molecule natural products described to date. Sponge-derived molecules, such as the chemotherapeutic eribulin, the calcium-channel blocker manoalide, and antimalarial compound kalihinol A, are renowned for their impressive medicinal, chemical, and biological properties.
Sheila Podell +2 more
exaly +4 more sources
Marine Sponges as Pharmacy [PDF]
Marine Biotechnology, 2005 Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here.
Sipkema, D. +4 more
openaire +2 more sources
Marine Sponges as a Drug Treasure [PDF]
Biomolecules & Therapeutics, 2016 Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge's derived compounds to examine its pharmacological properties.
Anjum, Komal +5 more
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Ecology of Antarctic Marine Sponges: An Overview [PDF]
Integrative and Comparative Biology, 2005 Sponges are important components of marine benthic communities of Antarctica. Numbers of species are high, within the lower range for tropical latitudes, similar to those in the Arctic, and comparable or higher than those of temperate marine environments.
McClintock, J.B. +3 more
openaire +4 more sources
Marine sponges in the once and future ocean [PDF]
Global Change Biology, 2022 Animals originated under hypoxia-low-oxygen conditions that are currently expanding throughout the global ocean. How marine sponges respond to hypoxia is both relevant to reconstructing early animal evolution and for forecasting the fate of modern marine ecosystems.
Daniel B. Mills, Erik A. Sperling
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Microbial Diversity of Marine Sponges [PDF]
, 2003 The recent application of molecular microbial ecology tools to sponge-microbe associations has revealed a glimpse into the biodiversity of these microbial communities, that is considered just 'the tip of the iceberg'. This chapter provides an overview over these new findings with regard to identity, diversity and distribution patterns of sponge ...
U, Hentschel +6 more
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Kinase Inhibitors from Marine Sponges [PDF]
Marine Drugs, 2011 Protein kinases play a critical role in cell regulation and their deregulation is a contributing factor in an increasing list of diseases including cancer. Marine sponges have yielded over 70 novel compounds to date that exhibit significant inhibitory activity towards a range of protein kinases.
Skropeta, Danielle +2 more
openaire +4 more sources
The Chemistry of Marine Sponges∗
, 2012 Marine sponges continue to attract wide attention from marine natural product chemists and pharmacologists alike due to their remarkable diversity of bioactive compounds. Since the early days of marine natural products research in the 1960s, sponges have notoriously yielded the largest number of new metabolites reported per year compared to any other ...
Ebada, Sherif S., Proksch, Peter
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EDIS, 2009 SGEF-169, a 4-page fact sheet by John Stevely and Don Sweat, describes why study and management of sponge populations remains essential to the health of Florida’s coastal waters and discusses their potential pharmaceutical value, harvesting practices, their history, biology, and other interesting facts.
John Stevely, Don Sweat
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Sponge symbionts and the marine P cycle [PDF]
Proceedings of the National Academy of Sciences, 2015 Marine sponges are ubiquitous colonizers of shallow, clear-water environments in the oceans (1, 2). Sponges have emerged as significant mediators of biogeochemical fluxes in coastal zones by virtue of respiring organic matter and facilitating both the consumption and release of nutrients (3, 4).
openaire +2 more sources