Results 1 to 10 of about 15,423 (166)

Terpene biosynthesis in marine sponge animals [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2023
Sea sponges are the largest marine source of small-molecule natural products described to date. Sponge-derived molecules, such as the chemotherapeutic eribulin, the calcium-channel blocker manoalide, and antimalarial compound kalihinol A, are renowned for their impressive medicinal, chemical, and biological properties.
Kayla Wilson, Tristan De Rond, Immo Burkhardt   +2 more
exaly   +4 more sources

Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures

mSystems, 2021
Marine sponge holobionts are prolific sources of natural products. One of the most geographically widespread classes of sponge-derived natural products is the bromotyrosine alkaloids.
Ipsita Mohanty, Subhasish Tapadar, Samuel G. Moore, Jason S. Biggs, Christopher J. Freeman, David A. Gaul, Neha Garg, Vinayak Agarwal   +7 more
doaj   +3 more sources

Cell interactions and osteogenic differentiation on marine sponge-derived scaffolds: a systematic review [PDF]

Biofunctional Materials, 2023
Marine sponges, with their unique blend of organic and inorganic components, hold promise as biomaterials for bone tissue engineering. In this study, we systematically reviewed and comprehensively analysed in vitro assays evaluating osteogenic cell ...
Jonas de Araújo Silva, Adriel Filipe Santos Braga da Silva, Amanda Sardeli Alqualo, Beatriz Viegas, Ana Cláudia Muniz Rennó, Renata Neves Granito   +5 more
doaj   +1 more source

Marine Sponges as Pharmacy [PDF]

Marine Biotechnology, 2005
Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here.
Sipkema, D., Franssen, M.C.R., Osinga, R., Tramper, J., Wijffels, R.H.   +4 more
openaire   +2 more sources

Microbiome species diversity and seasonal stability of two temperate marine sponges Hymeniacidon perlevis and Suberites massa

Environmental Microbiome, 2023
Background Marine sponges are diverse and functionally important members of marine benthic systems, well known to harbour complex and abundant symbiotic microorganisms as part of their species-specific microbiome.
Claire E. Lamb, Joy E. M. Watts
doaj   +1 more source

Sponges and Their Symbionts as a Source of Valuable Compounds in Cosmeceutical Field

Marine Drugs, 2021
In the last decades, the marine environment was discovered as a huge reservoir of novel bioactive compounds, useful for medicinal treatments improving human health and well-being.
Roberta Esposito, Nadia Ruocco, Thomas Viel, Serena Federico, Valerio Zupo, Maria Costantini   +5 more
doaj   +1 more source

Marine Sponge is a Promising Natural Source of Anti-SARS-CoV-2 Scaffold

Frontiers in Pharmacology, 2021
The current pandemic caused by SARS-CoV2 and named COVID-19 urgent the need for novel lead antiviral drugs. Recently, United States Food and Drug Administration (FDA) approved the use of remdesivir as anti-SARS-CoV-2.
Alshaimaa M. Hamoda, Alshaimaa M. Hamoda, Alshaimaa M. Hamoda, Bahgat Fayed, Bahgat Fayed, Naglaa S. Ashmawy, Naglaa S. Ashmawy, Abdel-Nasser A. El-Shorbagi, Abdel-Nasser A. El-Shorbagi, Rania Hamdy, Rania Hamdy, Sameh S. M. Soliman, Sameh S. M. Soliman   +12 more
doaj   +1 more source

Marine Sponges as a Drug Treasure [PDF]

Biomolecules & Therapeutics, 2016
Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge's derived compounds to examine its pharmacological properties.
Anjum, Komal, Abbas, Syed Qamar, Shah, Sayed Asmat Ali, Akhter, Najeeb, Batool, Sundas, Hassan, Syed Shams ul   +5 more
openaire   +2 more sources

Marine Sponges in a Snowstorm – Extreme Sensitivity of a Sponge Holobiont to Marine Oil Snow and Chemically Dispersed Oil Pollution

Frontiers in Microbiology, 2022
Holobionts formed by a host organism and associated symbionts are key biological units in marine ecosystems where they are responsible for fundamental ecosystem services. Therefore, understanding anthropogenic impacts on holobionts is essential. Sponges (
Johanne Vad, Laura Duran Suja, Stephen Summers, Theodore B. Henry, J. Murray Roberts   +4 more
doaj   +1 more source

Comparative Metagenomic Analysis of Biosynthetic Diversity across Sponge Microbiomes Highlights Metabolic Novelty, Conservation, and Diversification

mSystems, 2022
Marine sponges and their microbial symbiotic communities are rich sources of diverse natural products (NPs) that often display biological activity, yet little is known about the global distribution of NPs and the symbionts that produce them.
Catarina Loureiro, Anastasia Galani, Asimenia Gavriilidou, Maryam Chaib de Mares, John van der Oost, Marnix H. Medema, Detmer Sipkema   +6 more
doaj   +1 more source