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Producing drugs from marine sponges
Biotechnology Advances, 2003Marine sponges are potential sources of many unique metabolites, including cytotoxic and anticancer compounds. Natural sponge populations are insufficient or inaccessible for producing commercial quantities of metabolites of interest. This review focuses on methods of producing sponge biomass to overcome supply limitations.
Yusuf Chisti
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Marine Biotechnology, 1999
There is increasing interest in biotechnological production of marine sponge biomass owing to the discovery of many commercially important secondary metabolites in this group of animals. In this article, different approaches to producing sponge biomass are reviewed, and several factors that possibly influence culture success are evaluated.
Osinga, R., Tramper, J., Wijffels, R.H.
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There is increasing interest in biotechnological production of marine sponge biomass owing to the discovery of many commercially important secondary metabolites in this group of animals. In this article, different approaches to producing sponge biomass are reviewed, and several factors that possibly influence culture success are evaluated.
Osinga, R., Tramper, J., Wijffels, R.H.
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Sediment impacts on marine sponges
Marine Pollution Bulletin, 2015Changes in sediment input to marine systems can influence benthic environments in many ways. Sponges are important components of benthic ecosystems world-wide and as sessile suspension feeders are likely to be impacted by changes in sediment levels. Despite this, little is known about how sponges respond to changes in settled and suspended sediment ...
James J, Bell +6 more
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Haemagglutinins from Marine Sponges
Vox Sanguinis, 1968Summary. Two species of marine sponge, Cliona celata and Axinella sp. produce haemagglutinins and a third species, Tethya aurantium produces a haemolysin. A crude Axinella sp. preparation agglutinates goose erythrocytes at 0.5 μg/ml. The two haemagglutinins differ from each other in their relative activities against erythrocytes from a range of ...
R Y, Dodd, A P, MacLennan, D C, Hawkins
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Spongian diterpenoids from marine sponges
Natural Product Reports, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Robert A, Keyzers +2 more
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Metabolites of the marine sponge
Tetrahedron Letters, 1980Abstract The major constituent of Plakortis zygompha was (Z)-7-methyl-4-octen-3-one 1 , a highly volatile, sweet-smelling oil. The sponge also contained several derivatives of 3-hydroxy-4-hydroxymethyl-4-pentenoic acid.
D.John Faulkner, B.N. Ravi
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Chinese Journal of Oceanology and Limnology, 2005
Sponges are the most primitive of multicellular animals, and are major pharmaceutical sources of marine secondary metabolites. A wide variety of new compounds have been isolated from sponges. In order to produce sufficient amounts of the compounds of the needed, it is necessary to obtain large amount of sponges.
Qu Yi +4 more
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Sponges are the most primitive of multicellular animals, and are major pharmaceutical sources of marine secondary metabolites. A wide variety of new compounds have been isolated from sponges. In order to produce sufficient amounts of the compounds of the needed, it is necessary to obtain large amount of sponges.
Qu Yi +4 more
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Biochemical Systematics and Ecology, 1982
Abstract The 42 identified carotenoids isolated from 36 different marine spontes may, from structural considerations, be divided into four groups; (a) native phytoplankton-type carotenoids; (b) intact carotenoids of possible zooplankton origin, 9c) intact carotenoids of probable bacterial of fungal origin; and (d) sponge metabolized carotenoids ...
Synnøve Liaaen-Jensen +4 more
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Abstract The 42 identified carotenoids isolated from 36 different marine spontes may, from structural considerations, be divided into four groups; (a) native phytoplankton-type carotenoids; (b) intact carotenoids of possible zooplankton origin, 9c) intact carotenoids of probable bacterial of fungal origin; and (d) sponge metabolized carotenoids ...
Synnøve Liaaen-Jensen +4 more
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Genomic insights into the marine sponge microbiome
Nature Reviews Microbiology, 2012Marine sponges (phylum Porifera) often contain dense and diverse microbial communities, which can constitute up to 35% of the sponge biomass. The genome of one sponge, Amphimedon queenslandica, was recently sequenced, and this has provided new insights into the origins of animal evolution.
Hentschel, Ute +3 more
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