Results 161 to 170 of about 979,174 (298)

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

Balancing Exploration and Exploitation Through a Sequential Hybrid of Roach Infestation and Mayfly Algorithms for Constrained Engineering Design Optimization

open access: yesAI &Innovation, EarlyView.
ABSTRACT Maintaining an effective balance between exploration and exploitation is essential during optimization processes, from mathematical functions to more complex problems such as constrained engineering design optimization, particularly when addressing highly nonlinear issues with numerous local optima and strict feasibility requirements.
Enrique Lizárraga   +3 more
wiley   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

open access: yesAngewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui   +9 more
wiley   +2 more sources

Income sharing for common pool resources with uncertain productivity

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract We address the interconnected issues of externalities in the use of a natural common‐pool resource system and adverse effects of environmental uncertainty on risk‐averse resource users. We set up a simple analytical model and derive conditions such that insurance by means of an income sharing mechanism mitigates externalities and hence ...
Claudia Kelsall   +2 more
wiley   +1 more source

VARE: Geometry-Anchored Bearing and Range Stabilization for USV Recovery. [PDF]

open access: yesSensors (Basel)
Chen C   +6 more
europepmc   +1 more source

Maritime security report. November 2000 [Commercial maritime drug smuggling]

open access: yes
Port and security programs being implemented in Colombia?s port facilities, maritime jurisdictions, and the marine intermodal shipping cycle are producing successful results against commercial maritime drug smuggling.
United States. Department of Transportation. Maritime Administration
core  

The International Association of Maritime Universities (IAMU) Conference Book 2024

open access: yes
This year’s conference illustrates a healthy and thriving community of academic scholarship within the broader maritime education and training (MET) community that shapes the talent of future global maritime professionals.

core   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert   +31 more
wiley   +1 more source

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