Results 181 to 190 of about 1,328,349 (302)

pH‐Driven Two‐Stage Conformational Switching Activates an Acid‐Responsive Chaperone

open access: yesAngewandte Chemie, EarlyView.
AchC is an ATP‐independent, pH‐responsive chaperone. AchC functions as a molecular switch, sensing pH changes and undergoing a two‐stage conformational transition: C‐terminal extension (colored in yellow) loosening at mild pH 4.0–5.5 and monomerization at strong acidic pH 3.0.
Soojeong Ham   +4 more
wiley   +2 more sources

Maritime security report. November 2000 [Commercial maritime drug smuggling]

open access: yes
Port and security programs being implemented in Colombia?s port facilities, maritime jurisdictions, and the marine intermodal shipping cycle are producing successful results against commercial maritime drug smuggling.
United States. Department of Transportation. Maritime Administration
core  

Numerical simulation of oil spill dispersion and weathering in the Alboran Sea: A case study of its North-Eastern Coast. [PDF]

open access: yesPLoS One
Nouayti A   +11 more
europepmc   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert   +31 more
wiley   +1 more source

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