Results 71 to 80 of about 270,114 (335)

A microsatellite marker for yellow rust resistance in wheat [PDF]

open access: yes, 2010
Bulk segregant analysis (BSA) was used to identify molecular markers associated with yellow rust disease resistance in wheat (Triticum aestivum L.). DNAs isolated from the selected yellow rust tolerant and susceptible F-2 individuals derived from a cross
A. Uncuoglu   +38 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Searching for an Accurate Marker-Based Prediction of an Individual Quantitative Trait in Molecular Plant Breeding

open access: yesFrontiers in Plant Science, 2017
Molecular plant breeding with the aid of molecular markers has played an important role in modern plant breeding over the last two decades. Many marker-based predictions for quantitative traits have been made to enhance parental selection, but the trait ...
Yong-Bi Fu   +4 more
doaj   +1 more source

High throughput phenotyping method for water use efficiency in rice under field conditions : [Abstract, P 6.04] [PDF]

open access: yes, 2009
A collaborative CIAT/Cirad project aims to create new improved upland rice germplasm for drought tolerance based on population improvement through recurrent selection (RS).
Audebert, Alain   +4 more
core  

Controlling the Overfitting of Heritability in Genomic Selection through Cross Validation. [PDF]

open access: yes, 2017
In genomic selection (GS), all the markers across the entire genome are used to conduct marker-assisted selection such that each quantitative trait locus of complex trait is in linkage disequilibrium with at least one marker.
Jia, Zhenyu
core   +2 more sources

A Population Genetics Model of Marker-Assisted Selection [PDF]

open access: yesGenetics, 1997
A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations. Formulas were derived to relate linkage disequilibrium in a population to the proportion of additive genetic variance used by MAS, and in turn to an extra improvement in genetic response over ...
Luo, Z.W., Thompson, R., Woolliams, John
openaire   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Characterization of Akirin 2 gene in Langshan chicken

open access: yesIndian Journal of Animal Sciences, 2014
Akirin play an important role not only in innate immune response but also in skeletal myogenesis. The chicken’s Akirin gene family only has Akirin 2. We detected the coding sequences of the Akirin 2 gene in a Chinese indigenous chicken (Langshan chicken)
LINJUN YAN   +4 more
doaj   +1 more source

Evaluation of sorghum grain quality for QTL analysis and Marker Assisted Recurrent Selection (MARS) : [P1121] [PDF]

open access: yes, 2014
Sorghum breeding in Mali mostly focuses on varieties for human consumption. Even if most of breeding efforts concentrate on productivity and adaptation, grain quality is a very important aspect to consider for improved material to be adopted and ...
Davrieux, Fabrice   +7 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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