Results 81 to 90 of about 3,775,501 (251)

Marker-Assisted Selection

, 2005
A method of selecting desirable individuals in a breeding scheme based on DNA molecular marker patterns instead of, or in addition to, their trait values. A tool that can help plant breeders select more efficiently for desirable crop traits.
Richardson, Kelley, Byrne, Patrick
core  

Testing water-soluble carbohydrate QTL effects in perennial ryegrass (Lolium perenne L.) by marker selection [PDF]

, 2010
Water-soluble carbohydrates (WSC) are an important factor determining the nutritional value of grass forage and development of genetic markers for selection of WSC traits in perennial ryegrass would benefit future breeding programmes.
Dolstra, O., Humphreys, M.O., Turner, L.B., Farrell, M.   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Simulation of marker-assisted recurrent selection in autogamous species

Crop Breeding and Applied Biotechnology, 2002
This work used computer simulation to evaluate marker-assisted selection (MAS) in recurrent selection of autogamous species. Base populations were simulated by crossing each of five inbred lines with two others.
Eduardo Bearzoti, Roland Vencovsky
doaj  

Marker assisted selection for seedlessness in table grape breeding [PDF]

, 2012
Seedlessness is one of the most appreciated traits in the table grape (Vitis vinifera L.). The development of new seedless varieties is expensive and time consuming, involving the generation and selection of thousands of hybrids each year.
Javier Ibáñez, Carreño, Juan, María Teresa de Andrés, Carreño, Iván, de Andrés, M.T. [0000-0003-0082-1784], José Miguel Martínez-Zapater, Carreño, J., Carreño, I., Ibáñez, J. [0000-0002-6286-5638], Vargas, A.M. [0000-0002-0785-7192], Iván Carreño, José Antonio Cabezas, Eda Karaagac, Cabezas Martínez, José Antonio, Alba M. Vargas, Cabezas, J.A. [0000-0002-4728-6072], Martínez-Zapater, José M., Juan Carreño, de Andrés, M. T., Vargas, Alba María, Karaagac, E., Martínez-Zapater, J.M. [0000-0001-7217-4454], Ibáñez Marcos, Javier, Cabezas, J.A., Ibáñez, J., de Andrés, M.T., Vargas, A.M., Martínez-Zapater, J.M.   +27 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Marker-Assisted Selection

, 2017
Marker-assisted selection (MAS) is a method of selecting desirable individuals in a breeding program based on molecular markers with or without consideration of their trait values.
Singh, V.K., Nayak, S.N., Varshney, R.K.
core   +2 more sources

Marker-assisted selection for biotic stress (Bacterial leaf blight and gall midge) tolerance in Bc4F4 generation of rice (Oryza sativa L.)

Electronic Journal of Plant Breeding, 2018
Bacterial blight (BB) of rice caused by the pathogen Xanthomonas oryzae pv. oryzae and the insect gall midge (GM) (Orseolia oryzae) are two major limitations of rice production.
Krishnakumar R and, N. Kumaravadivel
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Efficiency of marker assisted selection

, 1997
Genetic markers can be used in breeding programmes in a variety of ways. Here we emphasize marker assisted introgression in crossbred populations, and marker assisted selection in outbred populations. As marker typing costs reduce, the value of their use
Visscher, PM, Haley, CS, Mackinnon, M, C.S. Haley, M. Mackinnon, P.M. Visscher   +5 more
core   +1 more source