Results 81 to 90 of about 269,710 (304)

Methodology: ssb-MASS: a single seed-based sampling strategy for marker-assisted selection in rice

open access: yesPlant Methods, 2019
Background Integrated breeding approaches such as combining marker-assisted selection and rapid line fixation through single-seed-descent, can effectively increase the frequency of desirable alleles in a breeding program and increase the rate of genetic ...
Juan David Arbelaez   +10 more
doaj   +1 more source

Molecular Marker Technology for Crop Improvement

open access: yesAgronomy, 2020
Since the 1980s, agriculture and plant breeding have changed with the development of molecular marker technology. In recent decades, different types of molecular markers have been used for different purposes: mapping, marker-assisted selection ...
Jose Miguel Soriano
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Marker assisted backcross breeding in Maize Research Institute Zemun Polje [PDF]

open access: yesSelekcija i Semenarstvo, 2019
The backcross breeding is one of the most extensively used methods in different crop species. With the development of molecular genetics, molecular markers become widely used as a tool aiding conventional breeding.
Kostadinović Marija   +6 more
doaj  

Characterization of Akirin 2 gene in Langshan chicken

open access: yesIndian Journal of Animal Sciences, 2014
Akirin play an important role not only in innate immune response but also in skeletal myogenesis. The chicken’s Akirin gene family only has Akirin 2. We detected the coding sequences of the Akirin 2 gene in a Chinese indigenous chicken (Langshan chicken)
LINJUN YAN   +4 more
doaj   +1 more source

Molecular Markers and Marker-Assisted Selection in Crop Plants

open access: yes, 2017
Molecular markers have revolutionized the plant biotechnology and genetic studies because of their versatility. These markers include biochemical constituents like secondary metabolites and macromolecules, viz., proteins and deoxyribonucleic acids (DNA).
Kamaluddin   +8 more
semanticscholar   +1 more source

Genome-wide association study, genomic prediction and marker-assisted selection for seed weight in soybean (Glycinemax)

open access: yesTheoretical and Applied Genetics, 2015
Twenty-two loci for soybean SW and candidate genes conditioning seed development were identified; and prediction accuracies of GS and MAS were estimated through cross-validation and validation with unrelated populations.
Jiaoping Zhang   +3 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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